PMID- 22217365
OWN - NLM
STAT- MEDLINE
DCOM- 20120831
LR  - 20120423
IS  - 1532-8430 (Electronic)
IS  - 0022-0736 (Linking)
VI  - 45
IP  - 3
DP  - 2012 May-Jun
TI  - Optimized electrocardiographic criteria for prior inferior and anterior 
      myocardial infarction.
PG  - 209-13
LID - 10.1016/j.jelectrocard.2011.11.002 [doi]
AB  - BACKGROUND AND PURPOSE: The first purpose of the study was to optimize 
      empirically the detection of prior inferior myocardial infarction (IMI) and prior 
      anterior myocardial infarction (AMI) by electrocardiogram (ECG). The second 
      purpose was to compare the diagnostic performances of the new criteria with those 
      of 3 widely used commercial diagnostic ECG algorithms. MATERIALS AND METHODS: We 
      analyzed the digital ECG data from 1138 subjects with suspected coronary artery 
      disease in whom the presence or absence of prior IMI or AMI was documented by 
      coronary angiography and left ventriculography. We used receiver operating 
      characteristic curves to develop the new criteria for prior IMI and AMI using a 
      training set of 562 subjects and then tested their diagnostic performances using 
      a separate test set of 576 subjects. In both the training and test sets, we used 
      chi(2) test to compare the performances of the new criteria with those of 3 
      commercial computerized diagnostic algorithms. RESULTS: The best criterion for 
      prior IMI was the algebraic sum of the Q and T amplitudes in leads III and aVF. 
      Its sensitivities/specificities were 71%/98% and 74%/98% in the training and test 
      sets, respectively. The best criterion for prior AMI was the algebraic sum of the 
      Q, R, and T amplitudes minus the Q duration in leads V(2), V(3), and V(4). Its 
      sensitivities/specificities were 68%/98% and 65%/98% in the training and test 
      sets, respectively. In both the training and test sets, these diagnostic 
      performances were generally superior to those of the 3 commercial algorithms. 
      CONCLUSIONS: Using digital ECG data, we developed and tested new criteria for 
      prior IMI and AMI whose diagnostic performances are generally superior to each of 
      3 widely used commercial ECG diagnostic algorithms.
CI  - Copyright (c) 2012 Elsevier Inc. All rights reserved.
FAU - Warner, Robert A
AU  - Warner RA
AD  - Tigard Research Institute, Tigard, OR 97224, USA. hillwarner@frontier.com
FAU - Hill, Norma E
AU  - Hill NE
LA  - eng
PT  - Journal Article
DEP - 20120102
PL  - United States
TA  - J Electrocardiol
JT  - Journal of electrocardiology
JID - 0153605
SB  - IM
MH  - *Algorithms
MH  - Coronary Artery Disease/*complications/*diagnosis
MH  - Diagnosis, Computer-Assisted/*methods
MH  - Electrocardiography/*methods
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis/*etiology
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 2012/01/06 06:00
MHDA- 2012/09/01 06:00
CRDT- 2012/01/06 06:00
PHST- 2011/09/26 00:00 [received]
PHST- 2012/01/06 06:00 [entrez]
PHST- 2012/01/06 06:00 [pubmed]
PHST- 2012/09/01 06:00 [medline]
AID - S0022-0736(11)00508-5 [pii]
AID - 10.1016/j.jelectrocard.2011.11.002 [doi]
PST - ppublish
SO  - J Electrocardiol. 2012 May-Jun;45(3):209-13. doi: 
      10.1016/j.jelectrocard.2011.11.002. Epub 2012 Jan 2.