PMID- 22223160
OWN - NLM
STAT- MEDLINE
DCOM- 20120418
LR  - 20220318
IS  - 1542-233X (Electronic)
IS  - 1542-2321 (Print)
IS  - 1542-2321 (Linking)
VI  - 38
IP  - 2
DP  - 2012 Mar
TI  - Repeated measurements of the anterior segment during accommodation using long 
      scan depth optical coherence tomography.
PG  - 102-8
LID - 10.1097/ICL.0b013e318243e795 [doi]
AB  - OBJECTIVES: The aim was to determine the repeatability of ultralong scan depth 
      spectral-domain optical coherence tomography (SD-OCT) measurements of the ocular 
      anterior segment during accommodation. METHODS: The center wavelength of the 
      SD-OCT light source was 840 nm with a bandwidth of 50 nm. The ocular axial 
      resolution of the system was approximately 6.0 mum, and the scan depth was 7.2 mm 
      in air. Twenty eyes of 20 healthy subjects were imaged with a custom-built, 
      ultralong scan depth SD-OCT during 2 visits. The anterior segment images were 
      acquired during nonaccommodative and maximal accommodative states. After image 
      processing and correction, the true values of the morphometric dimensions of the 
      anterior eye were obtained. The variables of the two states from two visits were 
      compared. RESULTS: For the corrected anterior segment images, the variables did 
      not significantly differ from one visit to the next. The values of anterior 
      chamber depth, pupil diameter, and the radius of the lens anterior surface 
      curvature during accommodation were significantly smaller than those during the 
      nonaccommodative state. The lens thickness significantly increased with 
      accommodation. There was no significant difference in the posterior surface 
      curvature of the lens between the two states. CONCLUSIONS: Ultralong scan depth 
      SD-OCT holds promise for quantifying dimensional changes in the eye during 
      accommodation. The instrument demonstrated good repeatability of ocular anterior 
      segment dimensional measurements during accommodation.
FAU - Yuan, Yimin
AU  - Yuan Y
AD  - School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China.
FAU - Chen, Feng
AU  - Chen F
FAU - Shen, Meixiao
AU  - Shen M
FAU - Lu, Fan
AU  - Lu F
FAU - Wang, Jianhua
AU  - Wang J
LA  - eng
GR  - P30 EY014801/EY/NEI NIH HHS/United States
GR  - P30 EY014801-09/EY/NEI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Eye Contact Lens
JT  - Eye & contact lens
JID - 101160941
SB  - IM
MH  - Accommodation, Ocular/*physiology
MH  - Adult
MH  - Analysis of Variance
MH  - Anterior Eye Segment/*anatomy & histology
MH  - Female
MH  - Humans
MH  - Male
MH  - Reproducibility of Results
MH  - Tomography, Optical Coherence/*instrumentation/standards
PMC - PMC3362999
MID - NIHMS346903
EDAT- 2012/01/10 06:00
MHDA- 2012/04/19 06:00
PMCR- 2013/03/01
CRDT- 2012/01/07 06:00
PHST- 2012/01/07 06:00 [entrez]
PHST- 2012/01/10 06:00 [pubmed]
PHST- 2012/04/19 06:00 [medline]
PHST- 2013/03/01 00:00 [pmc-release]
AID - 10.1097/ICL.0b013e318243e795 [doi]
PST - ppublish
SO  - Eye Contact Lens. 2012 Mar;38(2):102-8. doi: 10.1097/ICL.0b013e318243e795.