PMID- 22226820
OWN - NLM
STAT- MEDLINE
DCOM- 20121105
LR  - 20220318
IS  - 1873-2542 (Electronic)
IS  - 0378-1135 (Linking)
VI  - 157
IP  - 1-2
DP  - 2012 May 25
TI  - Infectious agents associated with respiratory diseases in 125 farrow-to-finish 
      pig herds: a cross-sectional study.
PG  - 152-63
LID - 10.1016/j.vetmic.2011.12.015 [doi]
AB  - A study was carried out in 125 farrow-to-finish pig herds to assess the 
      relationships between pathogens involved in respiratory disorders and to relate 
      these findings to clinical signs of respiratory diseases and pneumonia and 
      pleuritis at slaughter. Clinical examination and sampling were carried out on 
      four different batches in each herd (pigs aged 4, 10, 16 and 22 weeks). 
      Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, swine influenza 
      viruses (SIV), porcine reproductive and respiratory syndrome virus (PRRSV) and 
      porcine circovirus type 2 (PCV2) were detected by serological or PCR tests. 
      Pneumonia-like gross lesions and pleuritis were scored at the slaughterhouse. The 
      results indicate that the percentage of pigs PCR-positive for PCV2 at 4, 10 and 
      16 weeks old was associated with the percentage of pigs PCR-positive for M. 
      hyopneumoniae at these ages. On the other hand, the percentage of pigs with 
      antibodies against PRRSV at 10, 16 and 22 weeks was positively correlated with 
      the percentage of pigs seropositive for M. hyopneumoniae at 22 weeks, with the 
      percentage of pigs with antibodies against SIV H1N1 and SIV H1N2 and the 
      percentage of pigs sero-positive for A. pleuropneumoniae serotype 2. The findings 
      also indicate that, within the five studied pathogens, M. hyopneumoniae, PRRSV 
      and SIV H1N1 are the major pathogens involved in pneumonia-like gross lesions 
      even though PCV2 may play a role. A. pleuropneumoniae serotype 2, in association 
      with PRRSV, is significantly associated with extensive pleuritis. Respiratory 
      diseases could be significantly reduced by implementing measures including 
      appropriate management practices to control these pathogens.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Fablet, C
AU  - Fablet C
AD  - Agence Nationale de Securite Sanitaire (Anses), Unite Epidemiologie et Bien-Etre 
      du Porc, B.P. 53, 22440 Ploufragan, France. christelle.fablet@anses.fr
FAU - Marois-Crehan, C
AU  - Marois-Crehan C
FAU - Simon, G
AU  - Simon G
FAU - Grasland, B
AU  - Grasland B
FAU - Jestin, A
AU  - Jestin A
FAU - Kobisch, M
AU  - Kobisch M
FAU - Madec, F
AU  - Madec F
FAU - Rose, N
AU  - Rose N
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20111219
PL  - Netherlands
TA  - Vet Microbiol
JT  - Veterinary microbiology
JID - 7705469
RN  - 0 (Antibodies, Bacterial)
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Actinobacillus Infections/diagnosis/epidemiology/veterinary
MH  - Actinobacillus pleuropneumoniae/*isolation & purification
MH  - Animals
MH  - Antibodies, Bacterial/blood
MH  - Antibodies, Viral/blood
MH  - Circoviridae Infections/diagnosis/epidemiology/veterinary
MH  - Circovirus/*isolation & purification
MH  - Cross-Sectional Studies
MH  - France/epidemiology
MH  - Influenza A Virus, H1N1 Subtype/*isolation & purification
MH  - Influenza A Virus, H1N2 Subtype
MH  - Mycoplasma hyopneumoniae/*isolation & purification
MH  - Orthomyxoviridae Infections/diagnosis/epidemiology/veterinary
MH  - Pleurisy/epidemiology/microbiology/veterinary/virology
MH  - Pleuropneumonia/epidemiology/microbiology/veterinary/virology
MH  - Porcine Reproductive and Respiratory Syndrome/diagnosis/epidemiology
MH  - Porcine respiratory and reproductive syndrome virus/*isolation & purification
MH  - Sus scrofa/microbiology/virology
MH  - Swine
MH  - Swine Diseases/diagnosis/epidemiology/*microbiology/*virology
EDAT- 2012/01/10 06:00
MHDA- 2012/11/06 06:00
CRDT- 2012/01/10 06:00
PHST- 2011/07/05 00:00 [received]
PHST- 2011/11/07 00:00 [revised]
PHST- 2011/12/12 00:00 [accepted]
PHST- 2012/01/10 06:00 [entrez]
PHST- 2012/01/10 06:00 [pubmed]
PHST- 2012/11/06 06:00 [medline]
AID - S0378-1135(11)00655-9 [pii]
AID - 10.1016/j.vetmic.2011.12.015 [doi]
PST - ppublish
SO  - Vet Microbiol. 2012 May 25;157(1-2):152-63. doi: 10.1016/j.vetmic.2011.12.015. 
      Epub 2011 Dec 19.