PMID- 22234009
OWN - NLM
STAT- MEDLINE
DCOM- 20121003
LR  - 20190608
IS  - 1677-6119 (Electronic)
IS  - 1677-5538 (Linking)
VI  - 37
IP  - 6
DP  - 2011 Nov-Dec
TI  - Does the duration of infertility affect semen parameters and pregnancy rate after 
      varicocelectomy? A retrospective study.
PG  - 745-50
AB  - OBJECTIVES: The most common indication for treatment of varicocele is still male 
      subfertility. The aim of this study was to explore the effect of infertility 
      duration on semen parameters and spontaneous pregnancy rate after 
      varicocelectomy. MATERIALS AND METHODS: The medical records of 183 infertile 
      patients with clinical varicocele were retrospectively reviewed. The patients 
      were divided into three groups according to the duration of infertility (group I, 
      1-3 years, group II, 3-6 years and group III, > 6 years). Total sperm motility 
      counts (TMCs) before and after varicocelectomy and spontaneous pregnancy rate 
      among these groups were statistically compared. RESULTS: The greatest changes, 
      regarding preoperative and postoperative TMCs and spontaneous pregnancy rate were 
      noticed between group I and III. Preoperative TMCs in group I and III was 15.2 +/- 
      1.2, 7.8 +/- 1.4, respectively (p < 0.05). Postoperative TMCs in group I and III 
      was 33.7 +/- 2.5, 25.2 +/- 1.9, respectively (p < 0.05). An overall spontaneous 
      pregnancy rate of 34.4% was achieved after inguinal varicocelectomy. The greatest 
      spontaneous pregnancy rate was achieved in Group I (37.3%), and the lowest 
      pregnancy rate in Group III (26.3%) (P < 0.05). CONCLUSIONS: Surgical 
      varicocelectomy improves the total sperm motility counts especially in patients 
      who have a TMCS more than 5 million and improves the spontaneous pregnancy rates. 
      The improvement in the spontaneous pregnancy rates after varicocelectomy 
      correlates negatively with the duration of infertility. Therefore, duration of 
      infertility should be considered in treating a patient with a varicocele as a 
      cause of infertility.
FAU - Al-Ghazo, Mohammed A
AU  - Al-Ghazo MA
AD  - King Abdullah university Hospital, Faculty of Medicine, Jordan University of 
      Science and technology, Irbid, Jordan. alghazo@just.edu.jo
FAU - Ghalayini, Ibrahim Fathi
AU  - Ghalayini IF
FAU - al-Azab, Rami S
AU  - al-Azab RS
FAU - Bani-Hani, Ibrahim
AU  - Bani-Hani I
FAU - Daradkeh, Mohammad S
AU  - Daradkeh MS
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Brazil
TA  - Int Braz J Urol
JT  - International braz j urol : official journal of the Brazilian Society of Urology
JID - 101158091
SB  - IM
MH  - Adult
MH  - Azoospermia/complications
MH  - Female
MH  - Humans
MH  - Infertility, Male/etiology/*surgery
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Postoperative Period
MH  - Pregnancy
MH  - *Pregnancy Rate
MH  - Preoperative Period
MH  - Retrospective Studies
MH  - *Semen Analysis
MH  - Sperm Count
MH  - Sperm Motility
MH  - Time Factors
MH  - Varicocele/complications/physiopathology/*surgery
MH  - Young Adult
EDAT- 2012/01/12 06:00
MHDA- 2012/10/04 06:00
CRDT- 2012/01/12 06:00
PHST- 2011/04/25 00:00 [accepted]
PHST- 2012/01/12 06:00 [entrez]
PHST- 2012/01/12 06:00 [pubmed]
PHST- 2012/10/04 06:00 [medline]
AID - IBJUv37n6a9 [pii]
AID - 10.1590/s1677-55382011000600010 [doi]
PST - ppublish
SO  - Int Braz J Urol. 2011 Nov-Dec;37(6):745-50. doi: 10.1590/s1677-55382011000600010.