PMID- 22256739
OWN - NLM
STAT- MEDLINE
DCOM- 20120614
LR  - 20170605
IS  - 2096-7993 (Print)
IS  - 2096-7993 (Linking)
VI  - 25
IP  - 18
DP  - 2011 Sep
TI  - [Clinical significance of MRP8 and cypA expression in laryngeal squamous cell 
      carcinoma tissues].
PG  - 834-6, 839
AB  - OBJECTIVE: To study differential expression of MRP8, CypA protein in the patients 
      of laryngeal squamous cell carcinoma (LSCC) and the relationship in the 
      development of LSCC. METHOD: Immunohistochemistry was used to detect the 
      expression of MRP8,CypA protein in LSCC tissues of 41 cases and matched 
      paraneoplastic normal tissues of 41 cases,with results compared to the clinical 
      data to determine significance. RESULT: The expression of MRP8, CypA protein in 
      carcinoma and normal tissues and composition of different positive grades were in 
      statistical significance (P < 0.01). The expression levels of MRP8 were no 
      significant correlations were identified against any parameter (age,sex and 
      cervical lymphatic metastasis) examined (P > 0.05), but related to pathological 
      stage (P < 0.05). CONCLUSION: MRP8 protein is on intimate terms with different 
      pathological differentiation stage of LSCC. MRP8, CypA protein may play an 
      important role in the development and progression of LSCC.
FAU - Feng, Mingliang
AU  - Feng M
AD  - Department of Otolaryngology, the First Affiliated Hospital of Chongqing Medical 
      University, Chongqing, 400016, China.
FAU - Zhou, Jianrong
AU  - Zhou J
FAU - Wei, Lianzhi
AU  - Wei L
FAU - Yu, Lin
AU  - Yu L
FAU - Dong, Pujiang
AU  - Dong P
LA  - chi
PT  - Journal Article
PL  - China
TA  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
JT  - Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical 
      otorhinolaryngology, head, and neck surgery
JID - 101303164
RN  - 0 (Calgranulin A)
RN  - EC 5.2.1.- (Cyclophilin A)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Calgranulin A/*metabolism
MH  - Carcinoma, Squamous Cell/*metabolism/pathology
MH  - Cyclophilin A/*metabolism
MH  - Female
MH  - Humans
MH  - Laryngeal Neoplasms/*metabolism/pathology
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Prognosis
EDAT- 2012/01/20 06:00
MHDA- 2012/06/15 06:00
CRDT- 2012/01/20 06:00
PHST- 2012/01/20 06:00 [entrez]
PHST- 2012/01/20 06:00 [pubmed]
PHST- 2012/06/15 06:00 [medline]
PST - ppublish
SO  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Sep;25(18):834-6, 839.