PMID- 22262677
OWN - NLM
STAT- MEDLINE
DCOM- 20130117
LR  - 20151119
IS  - 1465-3664 (Electronic)
IS  - 0142-6338 (Linking)
VI  - 58
IP  - 5
DP  - 2012 Oct
TI  - Predictors of attrition among children born in a PMTCT programme in Zimbabwe 
      followed up over 5 years.
PG  - 360-9
LID - 10.1093/tropej/fmr112 [doi]
AB  - Eliminating of paediatric HIV within prevention of mother to child transmission 
      (PMTCT) interventions rests on complete follow-up of all children. We report on 
      predictors of child attrition in the PMTCT cascade over 5 years where 1050 
      pregnant women were enrolled at 36 gestational weeks. Mother and child pairs were 
      followed up at birth, 6 weeks, 4 months, 9 months, and every 6 months thereafter 
      for 60 months. Higher attrition was observed for children of economically 
      advantaged, socially stable mothers regardless of HIV status, whereas compliance 
      was observed for children whose mothers tested positive for HIV-1, HSV-2 and 
      Syphilis. Low birthweight was associated with attrition regardless of maternal 
      HIV status. Five years predictors of attrition did not differ by maternal HIV 
      status, as HIV-exposed children succumbed to mortality and those not exposed were 
      loss to follow-up (LFU). Child follow-up is influenced more by maternal lifestyle 
      and health risks leading to retention of high-risk children in PMTCT programmes.
FAU - Kurewa, Nyaradzai E
AU  - Kurewa NE
AD  - Letten Foundation Research Center, No. 3 Everrette Close, Avondale, Harare, 263, 
      Zimbabwe. enkurewa@hotmail.com
FAU - Gumbo, Felicity Z
AU  - Gumbo FZ
FAU - Mapingure, Paul M
AU  - Mapingure PM
FAU - Munjoma, Marshall W
AU  - Munjoma MW
FAU - Chirenje, Mike Z
AU  - Chirenje MZ
FAU - Rusakaniko, Simbarashe
AU  - Rusakaniko S
FAU - Stray-Pedersen, Babill
AU  - Stray-Pedersen B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120119
PL  - England
TA  - J Trop Pediatr
JT  - Journal of tropical pediatrics
JID - 8010948
RN  - 0 (Anti-HIV Agents)
RN  - 99DK7FVK1H (Nevirapine)
SB  - IM
MH  - Adult
MH  - Anti-HIV Agents/administration & dosage/*therapeutic use
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Follow-Up Studies
MH  - Forecasting
MH  - HIV Infections/*drug therapy/prevention & control/transmission
MH  - Humans
MH  - Infant
MH  - Infant, Low Birth Weight
MH  - Infant, Newborn
MH  - *Infectious Disease Transmission, Vertical
MH  - *Lost to Follow-Up
MH  - Nevirapine/administration & dosage/*therapeutic use
MH  - *Patient Compliance
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*drug therapy/prevention & control/virology
MH  - Program Evaluation/*methods
MH  - Prospective Studies
MH  - Socioeconomic Factors
MH  - Surveys and Questionnaires
MH  - Urban Population
MH  - Zimbabwe
EDAT- 2012/01/21 06:00
MHDA- 2013/01/18 06:00
CRDT- 2012/01/21 06:00
PHST- 2012/01/21 06:00 [entrez]
PHST- 2012/01/21 06:00 [pubmed]
PHST- 2013/01/18 06:00 [medline]
AID - fmr112 [pii]
AID - 10.1093/tropej/fmr112 [doi]
PST - ppublish
SO  - J Trop Pediatr. 2012 Oct;58(5):360-9. doi: 10.1093/tropej/fmr112. Epub 2012 Jan 
      19.