PMID- 22267299 OWN - NLM STAT- MEDLINE DCOM- 20120719 LR - 20151119 IS - 1945-1997 (Electronic) IS - 0098-6151 (Linking) VI - 112 IP - 1 Suppl 1 DP - 2012 Jan TI - Initiating a glucagon-like peptide-1 receptor agonist in the management of type 2 diabetes mellitus. PG - S16-21 AB - Control of blood glucose levels and restoration of pancreatic islet function are among the goals of physicians seeking to improve outcomes in patients with type 2 diabetes mellitus (T2DM). A growing body of evidence supports the use of incretins to achieve these goals, and current guidelines recommend earlier and more frequent use of these agents. However, in patients with T2DM, treatment paradigms should always be individualized. The author discusses issues for physicians to consider when adjusting T2DM therapy, including patient comorbidities, glucose control patterns, and potential adverse effects. The importance of patient education and practical points for initiating a glucagon-like peptide-1 receptor agonist are also reviewed. FAU - Gavin, James R 3rd AU - Gavin JR 3rd AD - Healing Our Village, Inc, Lanham, Maryland, USA. jrgavin3@yahoo.com LA - eng PT - Journal Article PT - Review PL - United States TA - J Am Osteopath Assoc JT - The Journal of the American Osteopathic Association JID - 7503065 RN - 0 (Blood Glucose) RN - 0 (GLP1R protein, human) RN - 0 (Glucagon-Like Peptide-1 Receptor) RN - 0 (Hypoglycemic Agents) RN - 0 (Receptors, Glucagon) SB - IM MH - Blood Glucose/drug effects/metabolism MH - Diabetes Mellitus, Type 2/blood/*drug therapy MH - *Disease Management MH - Glucagon-Like Peptide-1 Receptor MH - Humans MH - Hypoglycemic Agents/*therapeutic use MH - Receptors, Glucagon/*agonists/blood EDAT- 2012/02/01 06:00 MHDA- 2012/07/20 06:00 CRDT- 2012/01/24 06:00 PHST- 2012/01/24 06:00 [entrez] PHST- 2012/02/01 06:00 [pubmed] PHST- 2012/07/20 06:00 [medline] AID - 112/1_suppl_1/S16 [pii] PST - ppublish SO - J Am Osteopath Assoc. 2012 Jan;112(1 Suppl 1):S16-21.