PMID- 22268351
OWN - NLM
STAT- MEDLINE
DCOM- 20121015
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 29
IP  - 10
DP  - 2011 Oct
TI  - [Determination of virginiamycin M1, in feeds by ultra high performance liquid 
      chromatography-tandem mass spectrometry].
PG  - 962-6
AB  - A comprehensive analytical method based on ultra high performance liquid 
      chromatography-tandem mass spectrometry (UPLC-MS/MS) has been developed for the 
      determination of virginiamycin M1 in feeds. The sample was extracted twice by 
      ultrasonic extraction with ace-tonitrile-0.2% (v/v) formic acid (8:2, v/v). The 
      chromatographic separation was achieved with a BEH C18 column and acetonitrile-0. 
      3% (v/v) formic acid (35: 65, v/v) as the mobile phase. The identification and 
      quantification of the analyte were carried out on electrospray ionization MS/MS 
      in a multiple reaction monitoring (MRM) mode. The correlation coefficient (r) of 
      virginiamycin M1 was 0. 999 5 in the linear range of 0. 3 -226. 6 microg/L. The 
      detection limit (S/ N = 3) and quantification limit (S/N = 10) of virginiamycin 
      M1 were 2 microg/kg and 7 microg/kg, respectively. The average spiked recoveries 
      were in the range of 82. 6% to 102. 7% with the relative standard deviations 
      (RSDs) of 0.9% - 10.5%. The results demonstrate that the proposed method is 
      simple, sensitive, repeatable and suitable for the testing of virginiamycin M, in 
      feeds.
FAU - Huang, Yonghui
AU  - Huang Y
AD  - National Quality Supervision and Testing Center for Processed Food, Fujian 
      Inspection and Research Institute for Product Quality, Fuzhou 350002, China. 
      huangyonghui1982@163.com
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Anti-Bacterial Agents)
RN  - 8W4UOL59AZ (Streptogramin A)
SB  - IM
MH  - Animal Feed/*analysis
MH  - Animals
MH  - Anti-Bacterial Agents/analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Food Contamination/*prevention & control
MH  - Streptogramin A/*analysis
MH  - Tandem Mass Spectrometry/*methods
EDAT- 2012/01/25 06:00
MHDA- 2012/10/16 06:00
CRDT- 2012/01/25 06:00
PHST- 2012/01/25 06:00 [entrez]
PHST- 2012/01/25 06:00 [pubmed]
PHST- 2012/10/16 06:00 [medline]
PST - ppublish
SO  - Se Pu. 2011 Oct;29(10):962-6.