PMID- 22270350
OWN - NLM
STAT- MEDLINE
DCOM- 20120629
LR  - 20120314
IS  - 1095-9572 (Electronic)
IS  - 1053-8119 (Linking)
VI  - 60
IP  - 2
DP  - 2012 Apr 2
TI  - Reduced caudate volume and enhanced striatal-DMN integration in chess experts.
PG  - 1280-6
LID - 10.1016/j.neuroimage.2012.01.047 [doi]
AB  - The superior capability of chess experts largely depends on quick automatic 
      processing skills which are considered to be mediated by the caudate nucleus. We 
      asked whether continued practice or rehearsal of the skill over a long period of 
      time can lead to structural changes in this region. We found that, comparing to 
      novice controls, grandmaster and master level Chinese chess players (GM/Ms), who 
      had a mean period of over 10years of tournament and training practice, exhibited 
      significant smaller gray-matter volume in the bilateral caudate nuclei. When 
      these regions were used as seeds in functional connectivity analysis in 
      resting-state fMRI, significantly enhanced integration was found in GM/Ms between 
      the caudate and the default mode network (DMN), a constellation of brain areas 
      important for goal-directed cognitive performance and theory of mind. These 
      findings demonstrate the structural changes in the caudate nucleus in response to 
      its extensive engagement in chess problem solving, and its enhanced functional 
      integration with widely distributed circuitry to better support high-level 
      cognitive control of behavior.
CI  - Copyright A(c) 2012 Elsevier Inc. All rights reserved.
FAU - Duan, Xujun
AU  - Duan X
AD  - Key laboratory for Neuroinformation of Ministry of Education, School of Life 
      Science and Technology, University of Electronic Science and Technology of China, 
      Chengdu 610054, China.
FAU - He, Sheng
AU  - He S
FAU - Liao, Wei
AU  - Liao W
FAU - Liang, Dongmei
AU  - Liang D
FAU - Qiu, Lihua
AU  - Qiu L
FAU - Wei, Luqing
AU  - Wei L
FAU - Li, Yuan
AU  - Li Y
FAU - Liu, Chengyi
AU  - Liu C
FAU - Gong, Qiyong
AU  - Gong Q
FAU - Chen, Huafu
AU  - Chen H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120114
PL  - United States
TA  - Neuroimage
JT  - NeuroImage
JID - 9215515
SB  - IM
MH  - Adult
MH  - Caudate Nucleus/*anatomy & histology
MH  - Corpus Striatum/*physiology
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - *Mental Processes
MH  - Nerve Net/*physiology
MH  - Organ Size
MH  - *Play and Playthings
EDAT- 2012/01/25 06:00
MHDA- 2012/06/30 06:00
CRDT- 2012/01/25 06:00
PHST- 2011/08/13 00:00 [received]
PHST- 2012/01/03 00:00 [revised]
PHST- 2012/01/05 00:00 [accepted]
PHST- 2012/01/25 06:00 [entrez]
PHST- 2012/01/25 06:00 [pubmed]
PHST- 2012/06/30 06:00 [medline]
AID - S1053-8119(12)00064-X [pii]
AID - 10.1016/j.neuroimage.2012.01.047 [doi]
PST - ppublish
SO  - Neuroimage. 2012 Apr 2;60(2):1280-6. doi: 10.1016/j.neuroimage.2012.01.047. Epub 
      2012 Jan 14.