PMID- 22270379
OWN - NLM
STAT- MEDLINE
DCOM- 20130422
LR  - 20220310
IS  - 1476-5497 (Electronic)
IS  - 0307-0565 (Linking)
VI  - 36
IP  - 11
DP  - 2012 Nov
TI  - Type 2 diabetes mellitus and impaired glucose regulation in overweight and obese 
      children and adolescents living in Serbia.
PG  - 1479-81
LID - 10.1038/ijo.2011.273 [doi]
AB  - An increase in the prevalence of pediatric type 2 diabetes mellitus (T2DM) has 
      been reported by numerous studies in the United States during the past two 
      decades. Available data from Europe are scarce, but also suggest the rising 
      prevalence of this disease in overweight children. The aim of this study was to 
      determine the prevalence of previously undiagnosed T2DM, impaired fasting glucose 
      (IFG) and impaired glucose tolerance (IGT) in a clinic cohort of otherwise 
      healthy overweight and obese Caucasian children and adolescents living in Serbia. 
      The study group consisted of 301 subjects (176 girls, 125 boys) aged 5.2-18.9 
      years, with body mass index >90th percentile. Oral glucose tolerance test was 
      performed in all subjects. Previously undiagnosed T2DM was discovered in 0.3% 
      (n=1) and impaired glucose regulation in 15.9% (n=48) of the subjects. Isolated 
      IFG was detected in 4.3% (n=13), isolated IGT in 8.3% (n=25) and combined IFG and 
      IGT in 3.3% (n=10) of the subjects. Disturbances of glucose metabolism were 
      present in a substantial number of the subjects, which emphasizes the need for 
      prevention and treatment of childhood obesity.
FAU - Vukovic, R
AU  - Vukovic R
AD  - Department of Endocrinology, Mother and Child Health Care Institute of Serbia Dr 
      Vukan Cupic, Belgrade, Serbia. radevukovic9@gmail.com
FAU - Mitrovic, K
AU  - Mitrovic K
FAU - Milenkovic, T
AU  - Milenkovic T
FAU - Todorovic, S
AU  - Todorovic S
FAU - Zdravkovic, D
AU  - Zdravkovic D
LA  - eng
PT  - Journal Article
DEP - 20120124
PL  - England
TA  - Int J Obes (Lond)
JT  - International journal of obesity (2005)
JID - 101256108
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adolescent
MH  - Blood Glucose/*metabolism
MH  - Body Mass Index
MH  - Child
MH  - Child, Preschool
MH  - Diabetes Mellitus, Type 2/*blood/*epidemiology/prevention & control
MH  - Fasting/blood
MH  - Female
MH  - Glucose Intolerance/blood/*epidemiology
MH  - Glucose Tolerance Test
MH  - Humans
MH  - Male
MH  - Obesity/blood/epidemiology/prevention & control
MH  - Overweight/*blood/*epidemiology
MH  - Prevalence
MH  - Serbia/epidemiology
EDAT- 2012/01/25 06:00
MHDA- 2013/04/23 06:00
CRDT- 2012/01/25 06:00
PHST- 2012/01/25 06:00 [entrez]
PHST- 2012/01/25 06:00 [pubmed]
PHST- 2013/04/23 06:00 [medline]
AID - ijo2011273 [pii]
AID - 10.1038/ijo.2011.273 [doi]
PST - ppublish
SO  - Int J Obes (Lond). 2012 Nov;36(11):1479-81. doi: 10.1038/ijo.2011.273. Epub 2012 
      Jan 24.