PMID- 22272917 OWN - NLM STAT- MEDLINE DCOM- 20130117 LR - 20191210 IS - 1476-4954 (Electronic) IS - 1476-4954 (Linking) VI - 25 IP - 9 DP - 2012 Sep TI - Are there any differences in three-dimensional placental vascular indices obtained using conventional power Doppler and high-definition flow imaging? PG - 1664-7 LID - 10.3109/14767058.2012.657274 [doi] AB - OBJECTIVE: The purpose of this study was to determine whether there are differences in values and reproducibility of three-dimensional (3D) vascular indices obtained on placental volumes using power Doppler (PD) or high-definition flow imaging (HDFI) techniques. METHODS: A prospective study was performed on 121 uncomplicated singleton pregnancies at 11 + 0 to 13 + 6 weeks of gestation. Two placental volumes were acquired from each pregnancy. Vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were then analyzed and compared. In order to assess the reproducibility of the measurements, two additional placental volumes obtained with both PD and HDFI were acquired in 31 pregnancies and the agreement assessed by intraclass correlation coefficients. Inter-observer variability was assessed by analyzing all the volumes by two observers blinded to each other's. RESULTS: A significant relationship was observed between the vascular indices values obtained with the two techniques (VI Pearson's r=0.891 p<0.001; FI r=0.769 p<0.001; VFI r=0.847 p<0.001). The median values of VI, FI and VFI were significantly higher when obtained with HDFI imaging. In serial recordings, the ICCs resulted higher when volumes were acquired with HDFI rather than with PD techniques. Similarly, HDFI demonstrated a higher inter-observer reproducibility. CONCLUSIONS: 3D vascular indices calculated using HDFI are higher than those calculated using conventional PD. Although the relationship between the two methods is high, HDFI shows a better reproducibility suggesting its potential clinical application. FAU - Rizzo, Giuseppe AU - Rizzo G AD - Fetal Medicine Center Genoma, Universita di Roma "Tor Vergata", Rome, Italy. giuseppe.rizzo@uniroma2.it FAU - Pietrolucci, Maria Elena AU - Pietrolucci ME FAU - Aiello, Eloisa AU - Aiello E FAU - Dijmeli, Estelle AU - Dijmeli E FAU - Bosi, Costanza AU - Bosi C FAU - Arduini, Domenico AU - Arduini D LA - eng PT - Evaluation Study PT - Journal Article DEP - 20120214 PL - England TA - J Matern Fetal Neonatal Med JT - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians JID - 101136916 SB - IM MH - Adult MH - Blood Flow Velocity/physiology MH - Female MH - Gestational Age MH - Health Status Indicators MH - Humans MH - Imaging, Three-Dimensional/*methods MH - Observer Variation MH - Organ Size MH - Parity MH - Placenta/anatomy & histology/*blood supply/*diagnostic imaging MH - Pregnancy MH - Ultrasonography, Doppler, Duplex MH - Ultrasonography, Prenatal/*methods EDAT- 2012/01/26 06:00 MHDA- 2013/01/18 06:00 CRDT- 2012/01/26 06:00 PHST- 2012/01/26 06:00 [entrez] PHST- 2012/01/26 06:00 [pubmed] PHST- 2013/01/18 06:00 [medline] AID - 10.3109/14767058.2012.657274 [doi] PST - ppublish SO - J Matern Fetal Neonatal Med. 2012 Sep;25(9):1664-7. doi: 10.3109/14767058.2012.657274. Epub 2012 Feb 14.