PMID- 22273645
OWN - NLM
STAT- MEDLINE
DCOM- 20120514
LR  - 20120125
IS  - 1658-3175 (Electronic)
IS  - 0379-5284 (Linking)
VI  - 33
IP  - 1
DP  - 2012 Jan
TI  - Role of tissue Doppler imaging in assessing left ventricular diastolic 
      dysfunction severity. Does it hold the same ability?
PG  - 34-8
AB  - OBJECTIVE: To validate the diagnostic capability of tissue Doppler imaging in 
      assorting the extent of diastolic dysfunction. METHODS: In this primary clinical 
      research diagnostic study, we enrolled 70 patients with systemic hypertension 
      presenting with shortness of breath between May 2010 to July 2010 to Salmaniya 
      Medical Complex, Manama, Bahrain. Forty-eight patients satisfied the inclusion 
      criteria. They underwent extensive echocardiographic assessment of their 
      diastolic function with simultaneous NT pro-B-type natriuretic (BNP) assay. The 
      latter being the reference marker of diastolic defragment. RESULTS: Patients were 
      classified according to the severity of heart failure into 4 classes of New York 
      Heart Association (NYHA) Classification. Twenty-eight (58%) were males and 20 
      (42%) were females. The tissue Doppler imaging (TDI) maintained a steady positive 
      correlation with both NYHA functional class and the PRO-BNP titre. Correlation 
      coefficient was 0.8 with a p<0.0001. N-terminal pro-B-type natriuretic peptide 
      (NT-proBNP) can be calculated from simplified formula derived from the 
      correlation-pro-B-NP = 93.8 x (E/E')-940. CONCLUSION: The TDI can estimate the 
      severity of diastolic dysfunction with striking certainty and tremendous clinical 
      utility. Its limitation, however, has to be well addressed.
FAU - Al Bannay, Rashed A
AU  - Al Bannay RA
AD  - Cardiology Unit, Internal Medicine Department, Salmaniya Medical Complex, Manama, 
      Bahrain. abdullarashed@yahoo.com
FAU - Husain, Aysha A
AU  - Husain AA
LA  - eng
PT  - Journal Article
PL  - Saudi Arabia
TA  - Saudi Med J
JT  - Saudi medical journal
JID - 7909441
SB  - IM
MH  - *Diastole
MH  - Female
MH  - Heart Ventricles/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Severity of Illness Index
MH  - *Ultrasonography, Doppler
EDAT- 2012/01/26 06:00
MHDA- 2012/05/15 06:00
CRDT- 2012/01/26 06:00
PHST- 2012/01/26 06:00 [entrez]
PHST- 2012/01/26 06:00 [pubmed]
PHST- 2012/05/15 06:00 [medline]
AID - 0' [pii]
PST - ppublish
SO  - Saudi Med J. 2012 Jan;33(1):34-8.