PMID- 22273649
OWN - NLM
STAT- MEDLINE
DCOM- 20120514
LR  - 20120125
IS  - 1658-3175 (Electronic)
IS  - 0379-5284 (Linking)
VI  - 33
IP  - 1
DP  - 2012 Jan
TI  - Venous thromboembolism in a medical intensive care unit. The effect of 
      implementing clinical practice guidelines.
PG  - 55-60
AB  - OBJECTIVE: To determine the incidence of VTE in medical patients admitted to the 
      intensive care unit (ICU) following the implementation of a standard deep venous 
      thrombosis (DVT) prophylaxis protocol using unfractionated heparin (UFH), and to 
      identify risk factors for DVT in these patients. METHODS: We prospectively 
      studied 123 consecutive patients admitted to the Medical ICU of King Khalid 
      University Hospital, Riyadh, Saudi Arabia. We excluded patients on 
      anticoagulation or with contraindications for heparin. Patients who were negative 
      for DVT by screening Doppler Ultrasound (U/S) were started on UFH twice a day. 
      The Doppler U/S was repeated twice weekly for 6 weeks. RESULTS: One hundred and 
      four critically ill medical patients were included. A DVT was diagnosed in 10 
      patients while receiving UFH, an incidence rate of 9.8%. The compliance rate was 
      98%. Sepsis (p=0.0167), limited mobility (p<0.0001), previous DVT (p=0.024), and 
      nephrotic syndrome (p=0.008) were significantly more common in patients who 
      developed DVT compared with others. However, by backward logistic regression, 
      previous DVT was the only significant factor for the development of DVT 
      (B=-0.439, AOR=5.01, p<0.0001). CONCLUSION: The implementation of clinical 
      practice guidelines for VTE prophylaxis in critically ill medical patients using 
      UFH twice daily resulted in a high compliance rate and low incidence of VTE. 
      Previous DVT was a significant risk factor for development of VTE.
FAU - Al-Otair, Hadil A
AU  - Al-Otair HA
AD  - Department of Critical Care, King Khalid University Hospital, College of 
      Medicine, King Saud University, PO Box 2925 (95), Riyadh 11461, Kingdom of Saudi 
      Arabia. hadil.alotair@live.com
FAU - Khurshid, Syed M
AU  - Khurshid SM
FAU - Alzeer, Abdulaziz H
AU  - Alzeer AH
LA  - eng
PT  - Journal Article
PL  - Saudi Arabia
TA  - Saudi Med J
JT  - Saudi medical journal
JID - 7909441
RN  - 0 (Anticoagulants)
SB  - IM
MH  - Anticoagulants/*therapeutic use
MH  - Humans
MH  - *Intensive Care Units
MH  - Patient Compliance
MH  - *Practice Guidelines as Topic
MH  - Venous Thromboembolism/*drug therapy
EDAT- 2012/01/26 06:00
MHDA- 2012/05/15 06:00
CRDT- 2012/01/26 06:00
PHST- 2012/01/26 06:00 [entrez]
PHST- 2012/01/26 06:00 [pubmed]
PHST- 2012/05/15 06:00 [medline]
AID - 0' [pii]
PST - ppublish
SO  - Saudi Med J. 2012 Jan;33(1):55-60.