PMID- 22276640
OWN - NLM
STAT- MEDLINE
DCOM- 20130807
LR  - 20131121
IS  - 1525-1470 (Electronic)
IS  - 0736-8046 (Linking)
VI  - 30
IP  - 1
DP  - 2013 Jan-Feb
TI  - Febrile ulceronecrotic Mucha-Habermann disease with central nervous system 
      vasculitis.
PG  - 90-3
LID - 10.1111/j.1525-1470.2011.01669.x [doi]
AB  - Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a severe variant of 
      pityriasis lichenoides et varioliformis acuta (PLEVA). We report a case of FUMHD 
      in an 11-year-old boy who subsequently developed neurologic symptoms and was 
      found to have necrotizing vasculitis on brain biopsy. Over 5 years of follow-up, 
      he had one biopsy-proven recurrence of his skin lesions and continued 
      rehabilitation and treatment for residual neurologic complications. This case 
      provides histological evidence of central nervous system vasculitis associated 
      with FUMHD. Our patient's disease was eventually controlled with 
      cyclophosphamide.
CI  - (c) 2012 Wiley Periodicals, Inc.
FAU - Rosman, Ilana S
AU  - Rosman IS
AD  - Division of Dermatology, Department of Internal Medicine, School of Medicine 
      Washington University, and St. Louis Children's Hospital, St. Louis, Missouri 
      63110, USA.
FAU - Liang, Ling-Chih
AU  - Liang LC
FAU - Patil, Sushama
AU  - Patil S
FAU - Bayliss, Susan J
AU  - Bayliss SJ
FAU - White, Andrew J
AU  - White AJ
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20120126
PL  - United States
TA  - Pediatr Dermatol
JT  - Pediatric dermatology
JID - 8406799
RN  - X4W7ZR7023 (Methylprednisolone)
RN  - YL5FZ2Y5U1 (Methotrexate)
RN  - Febrile Ulceronecrotic Mucha-Habermann disease
SB  - IM
MH  - Biopsy, Needle
MH  - Child
MH  - Disease Progression
MH  - Drug Therapy, Combination
MH  - Herpes Simplex/diagnosis/*drug therapy/*pathology
MH  - Humans
MH  - Immunohistochemistry
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Methotrexate/therapeutic use
MH  - Methylprednisolone/therapeutic use
MH  - Monitoring, Physiologic
MH  - Pityriasis Lichenoides/diagnosis/*drug therapy/*pathology
MH  - Prognosis
MH  - Rare Diseases
MH  - Risk Assessment
MH  - Severity of Illness Index
MH  - Treatment Failure
MH  - Vasculitis, Central Nervous System/diagnosis/*drug therapy/*pathology
EDAT- 2012/01/27 06:00
MHDA- 2013/08/08 06:00
CRDT- 2012/01/27 06:00
PHST- 2012/01/27 06:00 [entrez]
PHST- 2012/01/27 06:00 [pubmed]
PHST- 2013/08/08 06:00 [medline]
AID - 10.1111/j.1525-1470.2011.01669.x [doi]
PST - ppublish
SO  - Pediatr Dermatol. 2013 Jan-Feb;30(1):90-3. doi: 10.1111/j.1525-1470.2011.01669.x. 
      Epub 2012 Jan 26.