PMID- 22279347
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20211021
IS  - 1998-3662 (Electronic)
IS  - 0971-4065 (Print)
IS  - 0971-4065 (Linking)
VI  - 22
IP  - 1
DP  - 2012 Jan
TI  - Treatment of gabapentin-induced myoclonus with continuous renal replacement 
      therapy.
PG  - 59-61
LID - 10.4103/0971-4065.83744 [doi]
AB  - A 56-year-old man with diabetes, hypertension, and chronic kidney disease 
      presented to the emergency room with a complaint of pain in his right foot. He 
      was found to have tremors. Gabapentin toxicity was suspected and the patient was 
      found to have high gabapentin level (6.3 mcg/ml). Patient was commenced on 
      continuous venovenous hemodiafiltration (CVVHD) and the pharmacokinetics of 
      gabapentin was studied. The patient improved symptomatically and his tremors 
      subsided. In this case report, we describe the successful management of 
      gabapentin toxicity with continuous renal replacement therapy and calculate the 
      clearance of gabapentin which will enable future treatment of gabapentin toxicity 
      by CVVHD.
FAU - Guddati, A K
AU  - Guddati AK
AD  - Department of Internal Medicine, Harlem Hospital Center, New York, USA.
FAU - Zafar, Z
AU  - Zafar Z
FAU - Cheng, J T
AU  - Cheng JT
FAU - Mohan, S
AU  - Mohan S
LA  - eng
PT  - Case Reports
PL  - India
TA  - Indian J Nephrol
JT  - Indian journal of nephrology
JID - 8914356
PMC - PMC3263068
OTO - NOTNLM
OT  - Clearance
OT  - dialysis
OT  - gabapentin
OT  - toxicity
COIS- Conflict of Interest: None declared.
EDAT- 2012/01/27 06:00
MHDA- 2012/01/27 06:01
PMCR- 2012/01/01
CRDT- 2012/01/27 06:00
PHST- 2012/01/27 06:00 [entrez]
PHST- 2012/01/27 06:00 [pubmed]
PHST- 2012/01/27 06:01 [medline]
PHST- 2012/01/01 00:00 [pmc-release]
AID - IJN-22-59 [pii]
AID - 10.4103/0971-4065.83744 [doi]
PST - ppublish
SO  - Indian J Nephrol. 2012 Jan;22(1):59-61. doi: 10.4103/0971-4065.83744.