PMID- 22287348
OWN - NLM
STAT- MEDLINE
DCOM- 20140123
LR  - 20120130
IS  - 1671-0274 (Print)
IS  - 1671-0274 (Linking)
VI  - 15
IP  - 1
DP  - 2012 Jan
TI  - [Duodenojejunal bypass in treatment for 7 cases with non-severe obese type 2 
      diabetes mellitus].
PG  - 36-8
AB  - OBJECTIVE: To investigate the efficacy and feasibility of duodenojejunal 
      bypass(DJB)on non-severe obese patients with type 2 diabetes mellitus(T2DM). 
      METHODS: The body mass index (BMI), fasting plasma glucose(FPG), 2h-postprandial 
      plasma glucose(2hPG), fasting insulin(F-ins), fasting c-peptide(F-CP), glycated 
      hemoglobin and hypoglycemic agents dose changes were tested in 7 patients with 
      non-severe obese T2DM undergoing DJB, preoperatively and within 24 weeks after 
      surgery during the follow-up. Data were collected and the clinical outcomes of 
      T2DM were analyzed. RESULTS: In 7 cases of non-obese T2DM who underwent DJB, one 
      patient was weaned off hypoglycemic agents with normal FPG, 2hPG and HbA1c 
      postoperatively. Five required significantly lower dosage. No significant 
      improvement in 1 case. Complete remission rate of hyperglycemia was 1/7, 
      effective rate was 6/7, and effective rate of HbA1c was 5/7. No significant 
      changes in BMI were observed between the preoperative and postoperative phases. 
      CONCLUSION: Plasma glucose level can be markedly reduced by duodenojejunal bypass 
      in non-obese T2DM, independent of weight loss, and the mechanism remains unclear.
FAU - Jiang, Fei-zhao
AU  - Jiang FZ
AD  - Department of Laparoscopic Surgery, Wenzhou Medical College, Zhejiang, Wenzhou, 
      China.
FAU - Zhu, Heng-liang
AU  - Zhu HL
FAU - Zheng, Xiao-feng
AU  - Zheng XF
FAU - Tu, Jin-fu
AU  - Tu JF
FAU - Lin, Hong
AU  - Lin H
FAU - Hu, Ru-ying
AU  - Hu RY
FAU - Chen, Xiong
AU  - Chen X
FAU - You, He-yi
AU  - You HY
FAU - Zhou, Zhen-xu
AU  - Zhou ZX
FAU - Zhang, Wei-Jian
AU  - Zhang WJ
FAU - Cai, Hua-Jie
AU  - Cai HJ
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhonghua Wei Chang Wai Ke Za Zhi
JT  - Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
JID - 101177990
SB  - IM
MH  - Adult
MH  - Aged
MH  - Bariatric Surgery/*methods
MH  - Diabetes Mellitus, Type 2/*surgery
MH  - Duodenum/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Jejunum/*surgery
MH  - Male
MH  - Middle Aged
MH  - Obesity
MH  - Treatment Outcome
EDAT- 2012/01/31 06:00
MHDA- 2014/01/24 06:00
CRDT- 2012/01/31 06:00
PHST- 2012/01/31 06:00 [entrez]
PHST- 2012/01/31 06:00 [pubmed]
PHST- 2014/01/24 06:00 [medline]
AID - 100003152011 [pii]
PST - ppublish
SO  - Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Jan;15(1):36-8.