PMID- 22293668
OWN - NLM
STAT- MEDLINE
DCOM- 20120522
LR  - 20190608
IS  - 1881-7122 (Electronic)
IS  - 0007-5124 (Linking)
VI  - 61
IP  - 1
DP  - 2012
TI  - Histological properties of the glomerular layer in the mouse accessory olfactory 
      bulb.
PG  - 13-24
AB  - In mammals, the vomeronasal system (VS) originating from the vomeronasal organ 
      (VNO; also called "Jacobson's organ") is considered to be a chemosensory system 
      that recognizes "pheromone" signals. In the accessory olfactory bulb (AOB), the 
      primary center of the VS, the glomerular cell layer (GL) of the AOB is regarded 
      as an important functional area in the transmission of pheromone signals from 
      vomeronasal sensory neurons (VSNs) of the VNO. In mice, the most frequently used 
      animal model for the study of the VS, the GL of the AOB has several unique 
      histological properties when compared with the main olfactory bulb (MOB): (i) 
      each glomerular size is far smaller than in the MOB; (ii) many juxtaglomerular 
      cells (JGCs) are GABA immunopositive, but subpopulations of cells distributed in 
      the AOB are tyrosine hydroxylase- or calcium-binding protein immunopositive; and 
      (iii) the dendritic branching pattern of the JGC in the AOB is heteromeric. The 
      biological significance of the mammalian VS is still debated. The unique 
      histological properties of the mouse AOB summerized in the present review may 
      give some useful information that may help in understanding the function of the 
      mammalian VS.
FAU - Yokosuka, Makoto
AU  - Yokosuka M
AD  - Department of Comparative and Behavioral Medicine, Nippon Veterinary and Life 
      Science University, Tokyo, Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Japan
TA  - Exp Anim
JT  - Experimental animals
JID - 9604830
RN  - 0 (Calcium-Binding Proteins)
RN  - 0 (Pheromones)
RN  - EC 1.14.16.2 (Tyrosine 3-Monooxygenase)
SB  - IM
MH  - Animals
MH  - Calcium-Binding Proteins/metabolism
MH  - Mice/*anatomy & histology/immunology/metabolism
MH  - Olfactory Bulb/*cytology/physiology
MH  - Pheromones/metabolism
MH  - Tyrosine 3-Monooxygenase/metabolism
MH  - Vomeronasal Organ/*cytology/physiology
EDAT- 2012/02/02 06:00
MHDA- 2012/05/23 06:00
CRDT- 2012/02/02 06:00
PHST- 2012/02/02 06:00 [entrez]
PHST- 2012/02/02 06:00 [pubmed]
PHST- 2012/05/23 06:00 [medline]
AID - JST.JSTAGE/expanim/61.13 [pii]
AID - 10.1538/expanim.61.13 [doi]
PST - ppublish
SO  - Exp Anim. 2012;61(1):13-24. doi: 10.1538/expanim.61.13.