PMID- 22295503
OWN - NLM
STAT- MEDLINE
DCOM- 20120214
LR  - 20201209
IS  - 1003-0034 (Print)
IS  - 1003-0034 (Linking)
VI  - 24
IP  - 11
DP  - 2011 Nov
TI  - [Progress of research between Helicobacter pylori infection and osteoporosis].
PG  - 966-8
AB  - Helicobacter pylori (HP) is an infectious pathogen which can easily infringe 
      gastric mucosa. If the body is infected by HP, it can release cytokines, such as 
      TNF-alpha, IL-1 and IL-6. These cytokines can regulate the absorption and 
      transformation of bone, promote the formation of osteoclast, and then cause 
      localized or systemic osteoporosis. HP infection may decrease the level of 
      estrogen and vitamin B12, which is considered as a risk factor for osteoporosis. 
      Helicobacter pylori infection is related with the occurrence of gastritis, peptic 
      ulcer and gastric malignancies, and these diseases and treatments are associated 
      with osteoporosis. Meanwhile the application of proton pump inhibitor (PPI) can 
      influence absorption of calcium, decrease the level of serum calcium and increase 
      the risk of fracture. Gastrostomy may cause bone metabolism disorders.
FAU - Xu, Zhong-hai
AU  - Xu ZH
AD  - Department of Orthopaedics, People's Hospital of Zhejiang Province, Hangzhou 
      310014, Zhejiang, China.
FAU - Zhang, Jun
AU  - Zhang J
FAU - Yang, Di
AU  - Yang D
FAU - Zhang, Jian-hua
AU  - Zhang JH
LA  - chi
PT  - Journal Article
PT  - Review
PL  - China
TA  - Zhongguo Gu Shang
JT  - Zhongguo gu shang = China journal of orthopaedics and traumatology
JID - 9815790
SB  - IM
MH  - Helicobacter Infections/*complications/drug therapy
MH  - *Helicobacter pylori
MH  - Humans
MH  - Osteoporosis/*etiology
EDAT- 2012/02/03 06:00
MHDA- 2012/02/15 06:00
CRDT- 2012/02/03 06:00
PHST- 2012/02/03 06:00 [entrez]
PHST- 2012/02/03 06:00 [pubmed]
PHST- 2012/02/15 06:00 [medline]
PST - ppublish
SO  - Zhongguo Gu Shang. 2011 Nov;24(11):966-8.