PMID- 22299460
OWN - NLM
STAT- MEDLINE
DCOM- 20120221
LR  - 20220321
IS  - 0125-1562 (Print)
IS  - 0125-1562 (Linking)
VI  - 42
IP  - 4
DP  - 2011 Jul
TI  - Impact of hookworm deworming on anemia and nutritional status among children in 
      Thailand.
PG  - 782-92
AB  - Hookworm infection is associated with anemia, especially among children and 
      deworming can improve anemic status; however, little information is available 
      about the degree to which anemia improves after deworming. We chose 
      hookworm-endemic rural areas of Thailand, Nan Province in the north, Kanchanaburi 
      Province in the west and Nakhon Si Thammarat Province in the south, to evaluate 
      this problem. Subjects were selected by primary school-based stool egg 
      examinations. Blood tests of 182 hookworm-positive primary school children, 
      composed of 22 heavy, 65 moderate and 95 light infections, were compared with a 
      control group of 57 children who were helminth-free both before and after 
      receiving deworming medicine. Before deworming, the red blood cell (RBC), 
      hemoglobin (Hb), hematocrit (Hct), mean corpuscular hemoglobin (MCH) and mean 
      corpuscular hemoglobin concentration (MCHC) and albumin levels of the 
      hookworm-infected groups were significantly lower than the helminth-free control 
      group. The Hb and Hct levels showed an inverse relationship with intensity of 
      hookworm infection. After deworming, the Hb, Hct, total protein and albumin 
      levels of the hookworm-infected children improved within 2 months to become 
      comparable with the helminth-free control group. One year after deworming, the 
      mean blood test results in the 2 groups were not significantly different from 
      each other.
FAU - Watthanakulpanich, Dorn
AU  - Watthanakulpanich D
AD  - Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, 
      Bangkok, Thailand.
FAU - Maipanich, Wanna
AU  - Maipanich W
FAU - Pubampen, Somchit
AU  - Pubampen S
FAU - Sa-Nguankiat, Surapol
AU  - Sa-Nguankiat S
FAU - Pooudouang, Somchai
AU  - Pooudouang S
FAU - Chantaranipapong, Yaovamarn
AU  - Chantaranipapong Y
FAU - Homsuwan, Nirundorn
AU  - Homsuwan N
FAU - Nawa, Yukifumi
AU  - Nawa Y
FAU - Waikagul, Jitra
AU  - Waikagul J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Thailand
TA  - Southeast Asian J Trop Med Public Health
JT  - The Southeast Asian journal of tropical medicine and public health
JID - 0266303
RN  - 0 (Anthelmintics)
RN  - 81G6I5V05I (Mebendazole)
RN  - F4216019LN (Albendazole)
SB  - IM
MH  - Adolescent
MH  - Albendazole/therapeutic use
MH  - Anemia/epidemiology/etiology/*physiopathology
MH  - Anthelmintics/therapeutic use
MH  - Child
MH  - Child, Preschool
MH  - Endemic Diseases
MH  - Female
MH  - Hookworm Infections/complications/*drug therapy/epidemiology
MH  - Humans
MH  - Male
MH  - Mebendazole/therapeutic use
MH  - Nutrition Surveys
MH  - *Nutritional Status
MH  - Rural Population
MH  - Thailand/epidemiology
EDAT- 2012/02/04 06:00
MHDA- 2012/02/22 06:00
CRDT- 2012/02/04 06:00
PHST- 2012/02/04 06:00 [entrez]
PHST- 2012/02/04 06:00 [pubmed]
PHST- 2012/02/22 06:00 [medline]
PST - ppublish
SO  - Southeast Asian J Trop Med Public Health. 2011 Jul;42(4):782-92.