PMID- 22301929
OWN - NLM
STAT- MEDLINE
DCOM- 20120409
LR  - 20230318
IS  - 1938-3207 (Electronic)
IS  - 0002-9165 (Print)
IS  - 0002-9165 (Linking)
VI  - 95
IP  - 3
DP  - 2012 Mar
TI  - Replacing caloric beverages with water or diet beverages for weight loss in 
      adults: main results of the Choose Healthy Options Consciously Everyday (CHOICE) 
      randomized clinical trial.
PG  - 555-63
LID - 10.3945/ajcn.111.026278 [doi]
AB  - BACKGROUND: Replacement of caloric beverages with noncaloric beverages may be a 
      simple strategy for promoting modest weight reduction; however, the effectiveness 
      of this strategy is not known. OBJECTIVE: We compared the replacement of caloric 
      beverages with water or diet beverages (DBs) as a method of weight loss over 6 mo 
      in adults and attention controls (ACs). DESIGN: Overweight and obese adults [n = 
      318; BMI (in kg/m(2)): 36.3 +/- 5.9; 84% female; age (mean +/- SD): 42 +/- 10.7 y; 54% 
      black] substituted noncaloric beverages (water or DBs) for caloric beverages 
      (>/=200 kcal/d) or made dietary changes of their choosing (AC) for 6 mo. RESULTS: 
      In an intent-to-treat analysis, a significant reduction in weight and waist 
      circumference and an improvement in systolic blood pressure were observed from 0 
      to 6 mo.Mean ((+/-SEM) weight losses at 6 mo were -2.5 +/- 0.45% in the DB group, 
      -2.03 +/- 0.40% in the water group, and -1.76 +/- 0.35% in the AC group; there were 
      no significant differences between groups [corrected]. The chance of achieving a 
      5% weight loss at 6 mo was greater in the DB group than in the AC group (OR: 
      2.29; 95% CI: 1.05, 5.01; P = 0.04). A significant reduction in fasting glucose 
      at 6 mo (P = 0.019) and improved hydration at 3 (P = 0.0017) and 6 (P = 0.049) mo 
      was observed in the Water group relative to the AC group. In a combined analysis, 
      participants assigned to beverage replacement were 2 times as likely to have 
      achieved a 5% weight loss (OR: 2.07; 95% CI: 1.02, 4.22; P = 0.04) than were the 
      AC participants. CONCLUSIONS: Replacement of caloric beverages with noncaloric 
      beverages as a weight-loss strategy resulted in average weight losses of 2% to 
      2.5%. This strategy could have public health significance and is a simple, 
      straightforward message. This trial was registered at clinicaltrials.gov as 
      NCT01017783.
FAU - Tate, Deborah F
AU  - Tate DF
AD  - Department of Nutrition, The University of North Carolina at Chapel Hill, Chapel 
      Hill, NC 27599-7440, USA. dtate@unc.edu
FAU - Turner-McGrievy, Gabrielle
AU  - Turner-McGrievy G
FAU - Lyons, Elizabeth
AU  - Lyons E
FAU - Stevens, June
AU  - Stevens J
FAU - Erickson, Karen
AU  - Erickson K
FAU - Polzien, Kristen
AU  - Polzien K
FAU - Diamond, Molly
AU  - Diamond M
FAU - Wang, Xiaoshan
AU  - Wang X
FAU - Popkin, Barry
AU  - Popkin B
LA  - eng
SI  - ClinicalTrials.gov/NCT01017783
GR  - P30 AG024832/AG/NIA NIH HHS/United States
GR  - P30 DK056350/DK/NIDDK NIH HHS/United States
GR  - R24 HD050924/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20120201
PL  - United States
TA  - Am J Clin Nutr
JT  - The American journal of clinical nutrition
JID - 0376027
RN  - 0 (Blood Glucose)
RN  - 059QF0KO0R (Water)
SB  - IM
EIN - Am J Clin Nutr. 2013 Dec;98(6):1599
MH  - Adult
MH  - *Beverages
MH  - Blood Glucose/analysis
MH  - Blood Pressure
MH  - Choice Behavior
MH  - Diet
MH  - Diet, Reducing/*methods
MH  - Energy Intake
MH  - Fasting/blood
MH  - *Feeding Behavior
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Interviews as Topic
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Obesity/*diet therapy
MH  - Patient Compliance
MH  - Single-Blind Method
MH  - Surveys and Questionnaires
MH  - Water
MH  - *Weight Loss
PMC - PMC3632875
EDAT- 2012/02/04 06:00
MHDA- 2012/04/10 06:00
PMCR- 2013/03/01
CRDT- 2012/02/04 06:00
PHST- 2012/02/04 06:00 [entrez]
PHST- 2012/02/04 06:00 [pubmed]
PHST- 2012/04/10 06:00 [medline]
PHST- 2013/03/01 00:00 [pmc-release]
AID - S0002-9165(23)01551-4 [pii]
AID - 026278 [pii]
AID - 10.3945/ajcn.111.026278 [doi]
PST - ppublish
SO  - Am J Clin Nutr. 2012 Mar;95(3):555-63. doi: 10.3945/ajcn.111.026278. Epub 2012 
      Feb 1.