PMID- 22302654 OWN - NLM STAT- MEDLINE DCOM- 20140220 LR - 20130522 IS - 1097-0347 (Electronic) IS - 1043-3074 (Linking) VI - 35 IP - 6 DP - 2013 Jun TI - Hyalinizing clear cell adenocarcinoma of the oropharynx. PG - E184-6 LID - 10.1002/hed.22940 [doi] AB - BACKGROUND: Hyalinizing clear cell adenocarcinoma (HCCA) is a rare salivary gland malignancy. To our knowledge, there are no published reports of primary clear cell carcinoma of the vallecula. METHODS: A 59-year-old man with progressive dysphagia and otalgia underwent direct laryngoscopy with biopsy of a vallecular mass. The pathology results returned as clear cell adenocarcinoma. He underwent a wide local excision for his T(2)N(0)M(0) stage II tumor. RESULTS: Clear cell adenocarcinoma of the oropharynx typically presents as a painless neck mass and it can be difficult to distinguish from other clear cell malignancies. CONCLUSION: Immunohistochemical staining is essential for narrowing the differential diagnosis of these lesions. Treatment is controversial but usually consists of wide local excision and possibly a neck dissection. CI - Copyright (c) 2012 Wiley Periodicals, Inc. FAU - Adil, Eelam AU - Adil E AD - Division of Otolaryngology-Head and Neck Surgery, Pennsylvania State University, Hershey, Pennsylvania 17033, USA. FAU - Setabutr, Dhave AU - Setabutr D FAU - Mikesell, Kael AU - Mikesell K FAU - Goldenberg, David AU - Goldenberg D LA - eng PT - Case Reports PT - Journal Article DEP - 20120202 PL - United States TA - Head Neck JT - Head & neck JID - 8902541 SB - IM MH - Adenocarcinoma, Clear Cell/*pathology/surgery MH - Deglutition Disorders/etiology MH - Earache/etiology MH - Humans MH - Male MH - Middle Aged MH - Oropharyngeal Neoplasms/*pathology/surgery EDAT- 2012/02/04 06:00 MHDA- 2014/02/22 06:00 CRDT- 2012/02/04 06:00 PHST- 2011/11/28 00:00 [accepted] PHST- 2012/02/04 06:00 [entrez] PHST- 2012/02/04 06:00 [pubmed] PHST- 2014/02/22 06:00 [medline] AID - 10.1002/hed.22940 [doi] PST - ppublish SO - Head Neck. 2013 Jun;35(6):E184-6. doi: 10.1002/hed.22940. Epub 2012 Feb 2.