PMID- 22311847
OWN - NLM
STAT- MEDLINE
DCOM- 20120518
LR  - 20160511
IS  - 2042-6984 (Electronic)
IS  - 2042-6976 (Linking)
VI  - 2
IP  - 1
DP  - 2012 Jan-Feb
TI  - Does food intolerance play a role in recurrent respiratory papillomatosis?
PG  - 85-8
LID - 10.1002/alr.20094 [doi]
AB  - BACKGROUND: The purpose of this study is to evaluate the potential role of food 
      intolerances in the management of recurrent respiratory papillomatosis (RRP). 
      METHODS: This is a retrospective case review of 4 pediatric patients with RRP. 
      All of the patients, cared for by the primary author between 2005 and 2010, were 
      managed using microdebrider resection, intralesional injection of cidofovir, and 
      required multiple surgeries. Skin prick test (SPT) and/or radioallergosorbent 
      test (RAST) were obtained for 2 patients. Oral food challenge was utilized in all 
      4 patients. RESULTS: Standard SPT and RAST did not identify any immunoglobulin E 
      (IgE)-based allergens. A detailed medical history followed by an oral food 
      challenge was successful at identifying food intolerances in all 4 patients. When 
      specific food elimination was implemented in these patients' treatments in 
      addition to microdebrider resection and cidofovir injection, statistically 
      significant long-term remissions were achieved. CONCLUSION: Food intolerance and 
      its impact on RRP and immune dysfunction deserve further investigation and may 
      benefit some patients with RRP.
CI  - Copyright (c) 2011 American Rhinologic Society-American Academy of Otolaryngic 
      Allergy, LLC.
FAU - Patel, Nalin J
AU  - Patel NJ
AD  - Tampa Ear Nose and Throat Associates, Tampa, FL 33613, USA. pedsent@gmail.com
FAU - Jenzarli, Ali
AU  - Jenzarli A
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20110915
PL  - United States
TA  - Int Forum Allergy Rhinol
JT  - International forum of allergy & rhinology
JID - 101550261
RN  - Recurrent respiratory papillomatosis
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Food Hypersensitivity/complications/*diet therapy
MH  - Humans
MH  - Papillomavirus Infections/*diet therapy/etiology
MH  - Respiratory Tract Infections/*diet therapy/etiology
MH  - Retrospective Studies
MH  - Treatment Outcome
EDAT- 2012/02/09 06:00
MHDA- 2012/05/19 06:00
CRDT- 2012/02/08 06:00
PHST- 2010/07/15 00:00 [received]
PHST- 2011/07/04 00:00 [revised]
PHST- 2011/08/02 00:00 [accepted]
PHST- 2012/02/08 06:00 [entrez]
PHST- 2012/02/09 06:00 [pubmed]
PHST- 2012/05/19 06:00 [medline]
AID - 10.1002/alr.20094 [doi]
PST - ppublish
SO  - Int Forum Allergy Rhinol. 2012 Jan-Feb;2(1):85-8. doi: 10.1002/alr.20094. Epub 
      2011 Sep 15.