PMID- 22313993
OWN - NLM
STAT- MEDLINE
DCOM- 20120720
LR  - 20151119
IS  - 0363-6771 (Print)
IS  - 0363-6771 (Linking)
VI  - 60
IP  - 1
DP  - 2012 Jan-Feb
TI  - Difficulty in diagnosing oral paracoccidioidomycosis after topical nystatin 
      usage.
PG  - e44-6
AB  - Paracoccidioidomycosis (PCM) is caused by a dimorphic fungus called 
      Paracoccidioides brasiliensis and is a disseminated, systemic disorder that 
      involves the lungs and other organs but presents characteristic oral lesions as 
      the prominent feature. This article reports an unusual case of a 56-year-old man 
      who had symptomatic granulomatous lesions in the oral cavity. The patient had 
      received a nystatin-based treatment that masked the presence of fungi and made 
      the diagnosis of PCM difficult. Although nystatin is normally used to treat oral 
      fungal infections such as candidiasis, its topical usage is not appropriate for 
      management of PCM. Once the patient received the correct treatment, he 
      demonstrated a full recovery.
FAU - Sperandio, Felipe Fornias
AU  - Sperandio FF
AD  - Department of Oral Pathology, University of Sao Paulo, SP, Brazil.
FAU - Giudice, Fernanda Salgueiredo
AU  - Giudice FS
FAU - Coelho, Ana Patricia Carneiro Goncalves Bezerra
AU  - Coelho AP
FAU - de Sousa, Suzana Cantanhede Orsini Machado
AU  - de Sousa SC
FAU - Martins, Marilia Triervelier
AU  - Martins MT
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Gen Dent
JT  - General dentistry
JID - 7610466
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Inflammatory Agents, Non-Steroidal)
RN  - 0 (Antifungal Agents)
RN  - 1400-61-9 (Nystatin)
RN  - 304NUG5GF4 (Itraconazole)
RN  - 6429L0L52Y (Dipyrone)
MH  - Anti-Bacterial Agents/*therapeutic use
MH  - Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
MH  - Antifungal Agents/*therapeutic use
MH  - Biopsy
MH  - Candidiasis, Oral/*drug therapy
MH  - Diagnosis, Differential
MH  - Dipyrone/therapeutic use
MH  - Follow-Up Studies
MH  - Humans
MH  - Itraconazole/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Mouth Diseases/*microbiology
MH  - Nystatin/*therapeutic use
MH  - Paracoccidioidomycosis/*diagnosis
EDAT- 2012/02/09 06:00
MHDA- 2012/07/21 06:00
CRDT- 2012/02/09 06:00
PHST- 2012/02/09 06:00 [entrez]
PHST- 2012/02/09 06:00 [pubmed]
PHST- 2012/07/21 06:00 [medline]
PST - ppublish
SO  - Gen Dent. 2012 Jan-Feb;60(1):e44-6.