PMID- 22315663 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20120823 LR - 20230502 IS - 2090-0058 (Electronic) IS - 2090-004X (Print) IS - 2090-004X (Linking) VI - 2012 DP - 2012 TI - Comparison of macular thickness in diabetic macular edema using spectral-domain optical coherence tomography and time-domain optical coherence tomography. PG - 959721 LID - 10.1155/2012/959721 [doi] LID - 959721 AB - Purpose. To compare the macular thicknesses in diabetic macular edema (DME) measured with spectral-domain optical coherence tomography (SD-OCT) and time-domain (TD) OCT. Patients and Methods. The average macular thicknesses of 50 eyes of 29 patients with DME were measured using SD-OCT and TD-OCT. Results. The mean macular thicknesses measured with TD-OCT and SD-OCT were 401.5 +/- 117.8 mum (mean +/- SD) and 446.2 +/- 123.5 mum, respectively. The macular thicknesses measured with the two devices were well correlated (Pearson's product moment correlation, r = 0.977, P < 0.001). A significant correlation was found between the best-corrected visual acuity and the retinal thickness measured by TD-OCT and SD-OCT (Pearson's product moment correlation, TD-OCT, r = 0.34; P < 0.05; SD-OCT, r = 0.32; P < 0.05). Discussion. The mean macular thickness measured with SD-OCT was about 45 mum thicker than that measured with TD-OCT. Attention should be paid when comparing data obtained using different OCT machines. FAU - Kakinoki, Masashi AU - Kakinoki M AD - Department of Ophthalmology, Shiga University of Medical Science, Seta-Tsukinowa-cho, 520-2192 Otsu, Japan. FAU - Miyake, Taichirou AU - Miyake T FAU - Sawada, Osamu AU - Sawada O FAU - Sawada, Tomoko AU - Sawada T FAU - Kawamura, Hajime AU - Kawamura H FAU - Ohji, Masahito AU - Ohji M LA - eng PT - Journal Article DEP - 20120118 PL - United States TA - J Ophthalmol JT - Journal of ophthalmology JID - 101524199 PMC - PMC3270434 EDAT- 2012/02/09 06:00 MHDA- 2012/02/09 06:01 PMCR- 2012/01/18 CRDT- 2012/02/09 06:00 PHST- 2011/04/04 00:00 [received] PHST- 2011/09/22 00:00 [revised] PHST- 2011/10/14 00:00 [accepted] PHST- 2012/02/09 06:00 [entrez] PHST- 2012/02/09 06:00 [pubmed] PHST- 2012/02/09 06:01 [medline] PHST- 2012/01/18 00:00 [pmc-release] AID - 10.1155/2012/959721 [doi] PST - ppublish SO - J Ophthalmol. 2012;2012:959721. doi: 10.1155/2012/959721. Epub 2012 Jan 18.