PMID- 22315931
OWN - NLM
STAT- MEDLINE
DCOM- 20120417
LR  - 20151119
IS  - 2154-4700 (Electronic)
IS  - 1933-8244 (Linking)
VI  - 67
IP  - 1
DP  - 2012
TI  - Eczema increases susceptibility to PM10 in office indoor environments.
PG  - 15-21
LID - 10.1080/19338244.2011.564236 [doi]
AB  - The objective was to compare impact of indoor office environment on employees 
      with eczema with those without eczema. Exposure was measured at 56 sites and 
      modelled for 173 work places. Tear film stability, lysozyme in nasal lavage, 
      immunoglobulin E (IgE), and Phadiatop were assessed, and symptoms and perceptions 
      collected by questionnaires. Multiple regression analyses were applied, adjusted 
      for age, gender, strain, current smoking, and respiratory infections. Those with 
      eczema perceived temperature too high but not associated with measured 
      temperature. They had increased lysozyme in nasal lavage associated with 
      increased air temperature difference between 6 and 10 AM, more general and 
      mucosal symptoms, and "dry or flushed facial skin" associated with airborne 
      particulate matter less than 10 microns in diameter (PM(10)). Impact of PM(10) 
      was most pronounced among those with eczema previous 30 days. Having eczema might 
      be an important predictor for subjective and objective responses to indoor 
      environment.
FAU - Bakke, Jan Vilhelm
AU  - Bakke JV
AD  - Department of Energy and Process Engineering, Norwegian University of Science and 
      Technology, Trondheim, Norway. Jan.Bakke@arbeidstilsynet.no
FAU - Wieslander, Gunilla
AU  - Wieslander G
FAU - Norback, Dan
AU  - Norback D
FAU - Moen, Bente E
AU  - Moen BE
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Arch Environ Occup Health
JT  - Archives of environmental & occupational health
JID - 101282564
RN  - 0 (Air Pollutants, Occupational)
RN  - 0 (Particulate Matter)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - EC 3.2.1.17 (Muramidase)
SB  - IM
MH  - Adult
MH  - Air Pollutants, Occupational/*adverse effects/analysis
MH  - Air Pollution, Indoor/*adverse effects/analysis
MH  - Case-Control Studies
MH  - Cross-Sectional Studies
MH  - Dermatitis, Atopic/immunology/*physiopathology
MH  - Facial Dermatoses/etiology
MH  - Female
MH  - Flushing/etiology
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Muramidase/metabolism
MH  - Nasal Lavage Fluid/chemistry
MH  - Occupational Exposure/*adverse effects/analysis
MH  - Particulate Matter/*adverse effects/analysis
MH  - Surveys and Questionnaires
MH  - Tears
MH  - Universities
MH  - Workplace
EDAT- 2012/02/10 06:00
MHDA- 2012/04/18 06:00
CRDT- 2012/02/10 06:00
PHST- 2012/02/10 06:00 [entrez]
PHST- 2012/02/10 06:00 [pubmed]
PHST- 2012/04/18 06:00 [medline]
AID - 10.1080/19338244.2011.564236 [doi]
PST - ppublish
SO  - Arch Environ Occup Health. 2012;67(1):15-21. doi: 10.1080/19338244.2011.564236.