PMID- 22324245 OWN - NLM STAT- MEDLINE DCOM- 20120308 LR - 20120213 IS - 1210-7913 (Print) IS - 1210-7913 (Linking) VI - 60 IP - 4 DP - 2011 Nov TI - [Cases of menstrual toxic shock syndrome in the Czech Republic in 1997-2011]. PG - 161-6 AB - AIM: To determine toxigenicity and other basic characteristics of 47 strains of Staphylococcus aureus referred to the National Reference Laboratory for Staphylococci (NRL) as suspected causative agents of menstrual toxic shock syndrome (MTSS). MATERIAL AND METHODS: S. aureus strains were collected from 11 administrative regions of the Czech Republic in 1997-2011. The diagnosis was based on phenotypic (reverse latex agglutination test) and genotypic (polymerase chain reaction) methods. RESULTS: Forty-four S. aureus strains were producers of toxic shock syndrome toxin 1 (TSST-1), either alone or in combination with staphylococcal enterotoxin. Three strains only produced enterotoxin (B, C, and H). CONCLUSION: MTSS is a serious multisystem disease. In this study, MTSS often had a severe course requiring intensive care. All MTSS patients used vaginal tampons that had been identified in the literature as a risk factor for MTSS. The case of MTSS in a 36-year-old woman caused by an enterotoxin H positive strain of S. aureus is probably the first to be reported in the world. FAU - Petras, P AU - Petras P AD - NRL pro stafylokoky, SZU Centrum epidemiologie a mikrobiologie, Praha. petrasi@szu.cz FAU - Machova, I AU - Machova I FAU - Ryskova, L AU - Ryskova L FAU - Prasil, P AU - Prasil P LA - cze PT - Case Reports PT - English Abstract PT - Journal Article TT - Pripady menstrualni formy syndromu toxickeho soku v Ceske republice v letech 1997-2011. PL - Czech Republic TA - Epidemiol Mikrobiol Imunol JT - Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne JID - 9431736 RN - 0 (Bacterial Toxins) RN - 0 (Enterotoxins) RN - 0 (Superantigens) RN - 0 (enterotoxin F, Staphylococcal) SB - IM MH - Adolescent MH - Adult MH - Bacterial Toxins/*biosynthesis MH - Czech Republic/epidemiology MH - Enterotoxins/*biosynthesis MH - Female MH - Humans MH - Menstrual Hygiene Products/microbiology MH - *Menstruation MH - Shock, Septic/epidemiology/*microbiology MH - Staphylococcal Infections/epidemiology/*microbiology MH - Staphylococcus aureus/classification/*metabolism MH - Superantigens/*biosynthesis MH - Young Adult EDAT- 2012/02/14 06:00 MHDA- 2012/03/09 06:00 CRDT- 2012/02/14 06:00 PHST- 2012/02/14 06:00 [entrez] PHST- 2012/02/14 06:00 [pubmed] PHST- 2012/03/09 06:00 [medline] PST - ppublish SO - Epidemiol Mikrobiol Imunol. 2011 Nov;60(4):161-6.