PMID- 22338552 OWN - NLM STAT- MEDLINE DCOM- 20120312 LR - 20171116 IS - 1128-3602 (Print) IS - 1128-3602 (Linking) VI - 16 IP - 1 DP - 2012 Jan TI - The prevalence of the metabolic syndrome and its impact on the left ventricular systolic function in the patients with non-diabetic first ST elevation myocardial infarction. PG - 90-5 AB - OBJECTIVE: Metabolic syndrome (MS) is common among the patients with myocardial infarction. The degree of the left ventricular systolic dysfunction is shown to be associated with poor prognosis after myocardial infarction. The aim of this study was to evaluate the prevalence of MS and its impact on the left ventricular systolic function in non-diabetic patients suffering first ST elevation myocardial infarction (STEMI). MATERIAL AND METHODS: This study was conducted prospectively in three centers. We included patients presenting with non-diabetic first acute STEMI. The systolic functions of the left ventricle were assessed through the ejection fraction, the wall motion score index (WMSI) and tissue Doppler myocardial S wave velocities. The diagnosis of MS was done based on the Adult Treatment Panel III clinical definition of the MS. RESULTS: Among the 240 patients, 90 patients (37.5%) had MS but 150 patients (62.5%) were free of the MS. The patients in the MS group were older and the prevalence was higher among the females. Mean myocardial S wave velocities were significantly lower in the patients with the MS in comparison to the patients without the MS (6.70 +/- 1.68 vs. 7.39 +/- 1.64; p < 0.01). LVEF and WMSI were similar in two groups. CONCLUSIONS: MS was highly common in nondiabetic patients with acute STEMI and left ventricular systolic function were more severely impaired in these patients. Our observations suggest that more severely impaired left ventricular systolic function after acute STEMI may contribute to the higher morbidity and mortality seen in the patients with MS after acute STEMI. FAU - Yazici, H U AU - Yazici HU AD - Department of Cardiology, Gazi University School of Medicine, Ankara, Turkey. drhyazici@gmail.com FAU - Poyraz, F AU - Poyraz F FAU - Turfan, M AU - Turfan M FAU - Sen, N AU - Sen N FAU - Tavil, Y AU - Tavil Y FAU - Tulmac, M AU - Tulmac M FAU - Vatankulu, M A AU - Vatankulu MA FAU - Aygul, N AU - Aygul N FAU - Ozdogru, I AU - Ozdogru I FAU - Abaci, A AU - Abaci A LA - eng PT - Journal Article PL - Italy TA - Eur Rev Med Pharmacol Sci JT - European review for medical and pharmacological sciences JID - 9717360 RN - 0 (Lipids) SB - IM MH - Aged MH - Aged, 80 and over MH - Electrocardiography MH - Female MH - Humans MH - Lipids/blood MH - Male MH - Metabolic Syndrome/complications/*epidemiology/*physiopathology MH - Middle Aged MH - Myocardial Infarction/complications/diagnostic imaging/*physiopathology MH - Ultrasonography MH - Ventricular Dysfunction, Left/physiopathology MH - Ventricular Function, Left/*physiology EDAT- 2012/02/18 06:00 MHDA- 2012/03/13 06:00 CRDT- 2012/02/18 06:00 PHST- 2012/02/18 06:00 [entrez] PHST- 2012/02/18 06:00 [pubmed] PHST- 2012/03/13 06:00 [medline] PST - ppublish SO - Eur Rev Med Pharmacol Sci. 2012 Jan;16(1):90-5.