PMID- 22348851 OWN - NLM STAT- MEDLINE DCOM- 20120420 LR - 20120221 IS - 0030-6002 (Print) IS - 0030-6002 (Linking) VI - 153 IP - 9 DP - 2012 Mar 4 TI - [Massive fundic gland polyposis caused by chronic proton pump inhibitor therapy]. PG - 351-6 LID - 10.1556/OH.2012.29313 [doi] AB - We report two cases of a massive fundic gland polyposis associated with protracted proton pump inhibitor (PPI) therapy. Both patients were females aged 51. On repeated endoscopy, the number of fundic gland polyps was increasing steeply, and they resulted in a passage disorder. In the first case, the enormous number of polyps made endoscopic removal impossible, so the patient was treated by total gastrectomy. Although our case is the second one reported in the world, we would like to draw the attention to this rare complication of long lasting PPI therapy. FAU - Hegedus, Ivett AU - Hegedus I AD - Pecsi Tudomanyegyetem, Altalanos Orvostudomanyi Kar Patologia Intezet. ivett.hegedus@kk.pte.hu FAU - Csizmadia, Csaba AU - Csizmadia C FAU - Lomb, Zoltan AU - Lomb Z FAU - Cseke, Laszlo AU - Cseke L FAU - Enkh-Amar, Yadamsuren AU - Enkh-Amar Y FAU - Pajor, Laszlo AU - Pajor L FAU - Bogner, Barna AU - Bogner B LA - hun PT - Case Reports PT - English Abstract PT - Journal Article PT - Review TT - Tartos protonpumpagatlo kezeles hatasara kialakulo massziv fundusmirigy-polyposis. PL - Hungary TA - Orv Hetil JT - Orvosi hetilap JID - 0376412 RN - 0 (Proton Pump Inhibitors) SB - IM MH - Female MH - *Gastrectomy MH - Gastric Fundus/drug effects/*pathology/surgery MH - Gastrointestinal Transit MH - Humans MH - Middle Aged MH - Polyps/*chemically induced/pathology/*surgery MH - Proton Pump Inhibitors/administration & dosage/*adverse effects MH - Stomach Diseases/*chemically induced/pathology/*surgery EDAT- 2012/02/22 06:00 MHDA- 2012/04/21 06:00 CRDT- 2012/02/22 06:00 PHST- 2012/02/22 06:00 [entrez] PHST- 2012/02/22 06:00 [pubmed] PHST- 2012/04/21 06:00 [medline] AID - C41723440N437257 [pii] AID - 10.1556/OH.2012.29313 [doi] PST - ppublish SO - Orv Hetil. 2012 Mar 4;153(9):351-6. doi: 10.1556/OH.2012.29313.