PMID- 22350229
OWN - NLM
STAT- MEDLINE
DCOM- 20121010
LR  - 20221207
IS  - 1432-2218 (Electronic)
IS  - 0930-2794 (Print)
IS  - 0930-2794 (Linking)
VI  - 26
IP  - 8
DP  - 2012 Aug
TI  - Impact of Roux-en-Y gastric bypass on regulation of diabetes type 2 in morbidly 
      obese patients.
PG  - 2202-7
LID - 10.1007/s00464-012-2160-4 [doi]
AB  - BACKGROUND: The idea of surgery as treatment for type 2 diabetes mellitus (T2DM) 
      was established in the US and was based on observation of patients after 
      bariatric surgery. Resolution of T2DM is observed within a few weeks after 
      surgery, in some cases even during hospitalization. The aim of this study was to 
      evaluate the impact of Roux-en-Y gastric bypass (RYGB) on diabetes in morbidly 
      obese patients. METHODS: We present 73 patients with T2DM who underwent 
      laparoscopic RYGB (LRYGB) to treat morbid obesity. In the group of 73 obese 
      patients (mean BMI = 42.3), there were 41 females and 32 males. RESULTS: 
      Regression of T2DM was observed in 51 patients (69.8%) while hospitalized. In 
      addition, 14 patients' (19.1%) glycemia and HBA1c stabilized within 12 weeks 
      after surgery (total regression rate of 88.9%). CONCLUSION: The ultimate 
      evaluation of this method of treating T2DM is still lacking and requires several 
      years of meticulous clinical studies. Despite that, considering the high cost of 
      life-long conservative therapy of T2DM and its complications and the severe 
      impact T2DM has on quality of life, surgical metabolic intervention may become 
      the most reasonable solution in many cases.
FAU - Proczko-Markuszewska, Monika
AU  - Proczko-Markuszewska M
AD  - Department of General, Endocrine and Transplant Surgery, Medical University of 
      Gdansk, Debinki 7 Street, 80-952 Gdansk, Poland. mproczko@gumed.edu.pl
FAU - Stefaniak, Tomasz
AU  - Stefaniak T
FAU - Kaska, Lukasz
AU  - Kaska L
FAU - Kobiela, Jarek
AU  - Kobiela J
FAU - Sledzinski, Zbigniew
AU  - Sledzinski Z
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20120221
PL  - Germany
TA  - Surg Endosc
JT  - Surgical endoscopy
JID - 8806653
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Adult
MH  - Blood Glucose/metabolism
MH  - Diabetes Mellitus, Type 2/blood/*surgery
MH  - Female
MH  - *Gastric Bypass
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Obesity, Morbid/*surgery
MH  - Prospective Studies
MH  - Treatment Outcome
MH  - Weight Loss
PMC - PMC3392505
EDAT- 2012/02/22 06:00
MHDA- 2012/10/12 06:00
PMCR- 2012/02/21
CRDT- 2012/02/22 06:00
PHST- 2011/08/24 00:00 [received]
PHST- 2012/01/03 00:00 [accepted]
PHST- 2012/02/22 06:00 [entrez]
PHST- 2012/02/22 06:00 [pubmed]
PHST- 2012/10/12 06:00 [medline]
PHST- 2012/02/21 00:00 [pmc-release]
AID - 2160 [pii]
AID - 10.1007/s00464-012-2160-4 [doi]
PST - ppublish
SO  - Surg Endosc. 2012 Aug;26(8):2202-7. doi: 10.1007/s00464-012-2160-4. Epub 2012 Feb 
      21.