PMID- 22351998
OWN - NLM
STAT- MEDLINE
DCOM- 20120410
LR  - 20131121
IS  - 0016-254X (Print)
IS  - 0016-254X (Linking)
VI  - 102
IP  - 11
DP  - 2011 Nov
TI  - [The application of fluorescence in situ hybridization to the peripheral-blood 
      preparations].
PG  - 318-24
AB  - The hematologic malignancy with specific chromosomal/genetic abnormality is 
      separately classified by the WHO classification of tumors hematopoietic and 
      lymphoid tissues. The chromosomal abnormalities, t (9; 22), t (8; 21), t (15; 17) 
      and inv (16) are especially important for the establishment of therapeutic 
      strategy and prognostication. We examined in this study, five cases were 
      analyzed, because abnormal cells were recognized by the differential white blood 
      count of the peripheral-blood and specific chromosomal abnormalities were 
      suspected. Whether peripheral-blood preparations after May-Grunwald Giemsa 
      staining could be used for fluorescence in situ hybridization (FISH). The fusion 
      signals were detected in the high rate by using a peripheral-blood specimen in 
      four cases, except for one case that had no specific chromosomal abnormality.
FAU - Ikuta, Mikihiro
AU  - Ikuta M
AD  - Division of Clinical Laboratory, Department of Medicine, Fukuoka University 
      Hospital, 7-45-1 Nanakuma, Jonan-ku, Fukuoka 814-0180 Japan. 
      mikuta@fukuoka-u.ac.jp
FAU - Ogami, Akiko
AU  - Ogami A
FAU - Takamatsu, Yasushi
AU  - Takamatsu Y
FAU - Anami, Kenichi
AU  - Anami K
FAU - Miura, Ikuo
AU  - Miura I
FAU - Kato, Junko
AU  - Kato J
FAU - Ishida, Hiromi
AU  - Ishida H
FAU - Futata, Yuko
AU  - Futata Y
FAU - Kawashima, Hironobu
AU  - Kawashima H
FAU - Matsunaga, Akira
AU  - Matsunaga A
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Fukuoka Igaku Zasshi
JT  - Fukuoka igaku zasshi = Hukuoka acta medica
JID - 9423321
RN  - 0 (May-Grunwald Giemsa)
RN  - T42P99266K (Methylene Blue)
RN  - TDQ283MPCW (Eosine Yellowish-(YS))
SB  - IM
MH  - Adult
MH  - Child
MH  - *Chromosome Aberrations
MH  - Eosine Yellowish-(YS)
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology
MH  - Leukemia, Promyelocytic, Acute/pathology
MH  - Methylene Blue
MH  - Precursor Cell Lymphoblastic Leukemia-Lymphoma/*pathology
EDAT- 2012/02/23 06:00
MHDA- 2012/04/11 06:00
CRDT- 2012/02/23 06:00
PHST- 2012/02/23 06:00 [entrez]
PHST- 2012/02/23 06:00 [pubmed]
PHST- 2012/04/11 06:00 [medline]
PST - ppublish
SO  - Fukuoka Igaku Zasshi. 2011 Nov;102(11):318-24.