PMID- 22354370
OWN - NLM
STAT- MEDLINE
DCOM- 20130201
LR  - 20220330
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 250
IP  - 10
DP  - 2012 Oct
TI  - Restoration of macular structure as the determining factor for macular hole 
      surgery outcome.
PG  - 1409-14
LID - 10.1007/s00417-012-1963-2 [doi]
AB  - OBJECTIVE: The aim of this work is to evaluate the preoperative and postoperative 
      spectral domain optical coherence tomography (SD-OCT) findings as predictors of 
      visual acuity for macular hole (MH) surgery. METHODS: Fifty eyes of 46 patients 
      diagnosed with MH and that had undergone 25-g vitrectomy with internal limiting 
      membrane peeling were included in this retrospective study. A complete clinical 
      examination and SD-OCT were performed before and after surgery. Three groups were 
      considered on the basis of the postoperative integrity of photoreceptor inner and 
      outer segment (IS-OS) junction and the external limiting membrane (ELM): group A 
      (11 eyes, both lines disrupted), group B (ten eyes, disrupted IS/OS line and 
      complete ELM), and group C (29 eyes, both lines restored). RESULTS: LogMAR BCVA 
      improved significantly after surgery from an average 0.60 +/- 0.29 to 0.19 +/- 0.19 
      (p < 0.01). No significant differences had been detected preoperatively among 
      these groups (p>/=0.18). Postoperative BCVA was significantly better in group C 
      compared to groups A and B (p </= 0.01). A significant correlation was found 
      between ELM restoration and postoperative BCVA (r = -0.63, p < 0.01), as well as 
      between IS/OS line restoration and postoperative BCVA (r = -0.55, p < 0.01). 
      CONCLUSIONS: Outer retina restoration seems to be the best determining factor for 
      a good visual rehabilitation after MH surgery.
FAU - Ruiz-Moreno, Jose Maria
AU  - Ruiz-Moreno JM
AD  - Department of Ophthalmology, Castilla La Mancha University, Albacete, Spain. 
      josemaria.ruiz@uclm.es
FAU - Lugo, Francisco
AU  - Lugo F
FAU - Montero, Javier A
AU  - Montero JA
FAU - Pinero, David P
AU  - Pinero DP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120223
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Basement Membrane/surgery
MH  - Epiretinal Membrane/surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Postoperative Period
MH  - Preoperative Period
MH  - ROC Curve
MH  - Retinal Perforations/*diagnosis/*physiopathology/surgery
MH  - Retinal Photoreceptor Cell Inner Segment/*pathology
MH  - Retinal Photoreceptor Cell Outer Segment/*pathology
MH  - Retrospective Studies
MH  - *Tomography, Optical Coherence
MH  - Treatment Outcome
MH  - Visual Acuity/*physiology
MH  - *Vitrectomy
EDAT- 2012/02/23 06:00
MHDA- 2013/02/05 06:00
CRDT- 2012/02/23 06:00
PHST- 2011/11/13 00:00 [received]
PHST- 2012/02/01 00:00 [accepted]
PHST- 2012/01/29 00:00 [revised]
PHST- 2012/02/23 06:00 [entrez]
PHST- 2012/02/23 06:00 [pubmed]
PHST- 2013/02/05 06:00 [medline]
AID - 10.1007/s00417-012-1963-2 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2012 Oct;250(10):1409-14. doi: 
      10.1007/s00417-012-1963-2. Epub 2012 Feb 23.