PMID- 22359728
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20220331
IS  - 2070-5204 (Electronic)
IS  - 1999-768X (Print)
IS  - 1999-768X (Linking)
VI  - 27
IP  - 1
DP  - 2012 Jan
TI  - Light chain deposition disease presenting as cholestatic jaundice: a case report.
PG  - 56-9
LID - 10.5001/omj.2012.12 [doi]
AB  - Light-chain deposition disease (LCDD) is characterized by tissue deposition of 
      the immunoglobulin light chains in multiple organs. These deposits appear similar 
      to amyloid on routine sections, but differ in their staining properties and 
      ultrastructural appearance. The deposits of LCCD are non -Congophilic and do not 
      exhibit a fibrillar ultrastructure; while, the proteinaceous substance seen in 
      primary amyloidosis is Congo red positive and fibrillar. One of the most common 
      organs to be involved in LCDD is the kidney. Earlier reports on cases of LCDD 
      have mostly shown simultaneous liver and renal involvement, there are very few 
      cases in the literature describing LCDD of the liver without renal involvement. 
      This report describes a patient who presented with severe cholestatic jaundice 
      and liver cell failure with normal renal function.
FAU - Kumar, Prasanna N
AU  - Kumar PN
CN  - Sandhya V
CN  - Venkatakrishnan L
CN  - Krishnaveni J
CN  - Mohanakrishnan A
CN  - Nirmala V
LA  - eng
PT  - Case Reports
PL  - Oman
TA  - Oman Med J
JT  - Oman medical journal
JID - 101526350
PMC - PMC3282131
OTO - NOTNLM
OT  - Cholestatic jaundice
OT  - Congo Red
OT  - Light Chains
EDAT- 2012/02/24 06:00
MHDA- 2012/02/24 06:01
PMCR- 2012/01/01
CRDT- 2012/02/24 06:00
PHST- 2011/09/16 00:00 [received]
PHST- 2011/11/14 00:00 [accepted]
PHST- 2012/02/24 06:00 [entrez]
PHST- 2012/02/24 06:00 [pubmed]
PHST- 2012/02/24 06:01 [medline]
PHST- 2012/01/01 00:00 [pmc-release]
AID - OMJ-D-11-00186 [pii]
AID - 10.5001/omj.2012.12 [doi]
PST - ppublish
SO  - Oman Med J. 2012 Jan;27(1):56-9. doi: 10.5001/omj.2012.12.