PMID- 22362518
OWN - NLM
STAT- MEDLINE
DCOM- 20130423
LR  - 20151119
IS  - 1795-990X (Electronic)
IS  - 0355-3140 (Linking)
VI  - 38
IP  - 6
DP  - 2012 Nov
TI  - The association between study characteristics and outcome in the relation between 
      job stress and cardiovascular disease - a multilevel meta-regression analysis.
PG  - 489-502
LID - 3283 [pii]
LID - 10.5271/sjweh.3283 [doi]
AB  - OBJECTIVES: Studies about job strain and cardiovascular disease (CVD) have 
      yielded inconsistent results, which hinders making a firm conclusion about the 
      association. Inconsistent findings may be the result of methodological 
      differences. If the relative CVD risk is influenced by methodological 
      differences, these differences should be explored in more detail in future 
      research to clarify which methodological characteristics are inherent to obtain 
      the most accurate estimate between job strain and CVD risk. By assessing how 
      study characteristics are associated with the outcome, we take the first step in 
      unraveling this association. In this review, we explore the following research 
      question: are study characteristics associated with the size of the reported 
      relative CVD risk? METHODS: A systematic literature search yielded 71 studies 
      about job stress, assessed with the demand-control model, and CVD. Traditional 
      meta-regression was extended enabling the use of correlated data to quantify 
      heterogeneity within and between studies. RESULTS: Compared to studies that use 
      the original Job Content Questionnaire (JCQ), studies in which a more deviant 
      form of the JCQ was used yielded, on average, 43% higher estimates. Studies 
      conducted in the USA yielded about 26% lower estimates compared to studies 
      conducted in Scandinavian countries. CONCLUSIONS: Several study characteristics 
      are associated with the size of the reported relative CVD risk. Many of these 
      study features are related to the validity of the exposure and outcome assessment 
      and are inherent to obtain an accurate estimate between work stress and CVD risk. 
      More research is needed to clarify why these study features impact the average 
      relative CVD risk.
FAU - Szerencsi, Karolina
AU  - Szerencsi K
AD  - Maastricht University, School CAPHRI, Department of Epidemiology, Maastricht, the 
      Netherlands. karolina.szerencsi@maastrichtuniversity.nl
FAU - van Amelsvoort, Ludovic G P M
AU  - van Amelsvoort LG
FAU - Viechtbauer, Wolfgang
AU  - Viechtbauer W
FAU - Mohren, Danielle C L
AU  - Mohren DC
FAU - Prins, Martin H
AU  - Prins MH
FAU - Kant, Ijmert
AU  - Kant I
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
DEP - 20120221
PL  - Finland
TA  - Scand J Work Environ Health
JT  - Scandinavian journal of work, environment & health
JID - 7511540
SB  - IM
MH  - *Burnout, Professional
MH  - Cardiovascular Diseases/complications/*psychology
MH  - Humans
MH  - Risk Factors
MH  - Scandinavian and Nordic Countries
MH  - Stress, Psychological/*complications
MH  - Surveys and Questionnaires
EDAT- 2012/03/01 06:00
MHDA- 2013/04/24 06:00
CRDT- 2012/02/25 06:00
PHST- 2012/02/25 06:00 [entrez]
PHST- 2012/03/01 06:00 [pubmed]
PHST- 2013/04/24 06:00 [medline]
AID - 3283 [pii]
AID - 10.5271/sjweh.3283 [doi]
PST - ppublish
SO  - Scand J Work Environ Health. 2012 Nov;38(6):489-502. doi: 10.5271/sjweh.3283. 
      Epub 2012 Feb 21.