PMID- 22367309
OWN - NLM
STAT- MEDLINE
DCOM- 20120703
LR  - 20120227
IS  - 0016-3813 (Print)
IS  - 0016-3813 (Linking)
VI  - 148
IP  - 1
DP  - 2012 Jan-Feb
TI  - [The role of population genetics of Mexico in transplant immunology].
PG  - 52-67
AB  - This review focuses on six transcendental aspects that affect transplant 
      immunology in Mexico: in first place, several immune factors which may lead to 
      graft loss are highlighted; then, some features of the biological variability 
      present in Mexican populations are pointed out in the context of their adaptive 
      and sociopolitical history, leading to the discussion on the genetic diversity 
      within the major histocompatibility complex (MHC) and the importance of 
      resolution in genotypic characterization of the human leukocyte antigen (HLA) and 
      related systems on the basis of human intra-population variability. Critical 
      points on the interpretation of serological reactivity of anti-HLA antibodies are 
      discussed in function of allelic frequency as a probability of finding a variant 
      in a finite population. Finally, evidence of influence of other genetic systems 
      on the recipient-graft relationship is emphasized.
FAU - Barquera Lozano, Rodrigo
AU  - Barquera Lozano R
AD  - Laboratorio de Genetica Molecular, Escuela Nacional de Antropologia e Historia, 
      Mexico. jrockdrigo@hotmail.com
LA  - spa
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - El papel de la genetica de poblaciones en la inmunologia del trasplante en 
      Mexico.
PL  - Mexico
TA  - Gac Med Mex
JT  - Gaceta medica de Mexico
JID - 0010333
RN  - 0 (Antibodies)
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Antibodies
MH  - Genetic Variation/immunology
MH  - *Genetics, Population
MH  - Genotyping Techniques
MH  - HLA Antigens/immunology
MH  - Humans
MH  - Mexico
MH  - Transplantation Immunology/*genetics
EDAT- 2012/03/01 06:00
MHDA- 2012/07/04 06:00
CRDT- 2012/02/28 06:00
PHST- 2012/02/28 06:00 [entrez]
PHST- 2012/03/01 06:00 [pubmed]
PHST- 2012/07/04 06:00 [medline]
PST - ppublish
SO  - Gac Med Mex. 2012 Jan-Feb;148(1):52-67.