PMID- 22372646
OWN - NLM
STAT- MEDLINE
DCOM- 20121203
LR  - 20131121
IS  - 1556-4029 (Electronic)
IS  - 0022-1198 (Linking)
VI  - 57
IP  - 4
DP  - 2012 Jul
TI  - Ecstasy and suicide.
PG  - 1137-9
LID - 10.1111/j.1556-4029.2012.02107.x [doi]
AB  - Deaths due to the ring-derivative amphetamines are not common and are usually 
      accidental involving dehydration and hyperthermia. Suicides from 
      3,4-methylenedioxymethamphetamine (MDMA) and related ring-derivative amphetamines 
      overdose are rare. A 15-year-old female who had a history of depression and 
      previous suicide attempts was found dead with a suicide note. Toxicology 
      demonstrated lethal serum concentrations of MDMA (9.3 mg/L), with 34 mg/kg of 
      MDMA in the liver, 2.4 mg/L in the urine, and 530 mg/kg in the stomach. The cause 
      of death was MDMA toxicity, the manner suicide. While MDMA may be detected in 
      victims in other drug-related or traumatic deaths, it is only rarely used in 
      isolation in suicide, with a predominance in the 21- to 25-year-old range. 
      Despite the rarity of such events, the possibility of a nonaccidental manner of 
      death should be considered when high levels of MDMA and associated amphetamines 
      are found at autopsy.
CI  - (c) 2012 American Academy of Forensic Sciences.
FAU - Fernando, Tarini
AU  - Fernando T
AD  - Discipline of Anatomy and Pathology, The University of Adelaide, Adelaide, SA 
      5005, Australia.
FAU - Gilbert, John D
AU  - Gilbert JD
FAU - Carroll, Christine M
AU  - Carroll CM
FAU - Byard, Roger W
AU  - Byard RW
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20120228
PL  - United States
TA  - J Forensic Sci
JT  - Journal of forensic sciences
JID - 0375370
RN  - 0 (Hallucinogens)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adolescent
MH  - Depression/psychology
MH  - Female
MH  - Forensic Pathology
MH  - Forensic Toxicology
MH  - Hallucinogens/analysis/*poisoning
MH  - Humans
MH  - Liver/chemistry
MH  - N-Methyl-3,4-methylenedioxyamphetamine/analysis/*poisoning
MH  - Prescription Drug Misuse
MH  - Stomach/chemistry
MH  - *Suicide
EDAT- 2012/03/01 06:00
MHDA- 2012/12/10 06:00
CRDT- 2012/03/01 06:00
PHST- 2012/03/01 06:00 [entrez]
PHST- 2012/03/01 06:00 [pubmed]
PHST- 2012/12/10 06:00 [medline]
AID - 10.1111/j.1556-4029.2012.02107.x [doi]
PST - ppublish
SO  - J Forensic Sci. 2012 Jul;57(4):1137-9. doi: 10.1111/j.1556-4029.2012.02107.x. 
      Epub 2012 Feb 28.