PMID- 22376194 OWN - NLM STAT- MEDLINE DCOM- 20120928 LR - 20221207 IS - 1464-5165 (Electronic) IS - 0963-8288 (Linking) VI - 34 IP - 19 DP - 2012 TI - Intensive aerobic cycling training with lower limb weights in Chinese patients with chronic stroke: discordance between improved cardiovascular fitness and walking ability. PG - 1665-71 LID - 10.3109/09638288.2012.658952 [doi] AB - PURPOSE: To evaluate the effect of aerobic cycling training with lower limb weights on cardiovascular fitness (peak VO(2)) and walking ability in chronic stroke survivors, and to investigate the relationship between changes in these parameters. METHODS: 133 Chinese patients with chronic hemiparetic stroke (mean age 58 years) were randomized to either 8-week (5x/week) aerobic cycling training with lower limb weights group (n = 68) or a low-intensity overground walking group (n = 65). Peak VO(2), 6-minute walk distance (6MWD), knee muscle strength, balance and spasticity were measured before and after intervention. RESULTS: Cycling training increased peak VO(2) (24% vs. 3%, p < 0.001), 6MWD (2.7% vs. 0.5%, p < 0.001), paretic (11% vs. 1.6%, p < 0.001) and nonparetic knee strength (16% vs. 1.0%, p < 0.001). In the cycling group, percent changes in peak VO(2) were positively associated with those in paretic (r = 0.491, p < 0.001) and nonparetic knee strength (r = 0.432, p < 0.001). Increased 6MWD correlated significantly with improved balance, spasticity and paretic knee strength by the stepwise regression analysis (r(2) = 0.342, p = 0.004), but not fitness gains. CONCLUSIONS: The enhanced cardiovascular fitness after aerobic cycling training in Chinese patients with chronic stroke is not associated with the increased walking ability. Unparallel improvements in these parameters related different determinants may have implications for intervention strategy. FAU - Jin, Hong AU - Jin H AD - Department of Cardiology, Zhongda Hospital, Southeast University, Nanjing, China. jinhong5985@163.com FAU - Jiang, Yibo AU - Jiang Y FAU - Wei, Qin AU - Wei Q FAU - Wang, Bilei AU - Wang B FAU - Ma, Genshan AU - Ma G LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20120301 PL - England TA - Disabil Rehabil JT - Disability and rehabilitation JID - 9207179 SB - IM MH - Aged MH - Aged, 80 and over MH - Asian People MH - *Bicycling MH - Cardiovascular System MH - Exercise Test MH - Exercise Therapy/*methods MH - Female MH - Heart Rate/physiology MH - Humans MH - Leg/physiopathology MH - Male MH - Middle Aged MH - Muscle Strength MH - Oxygen Consumption MH - Physical Fitness/*physiology MH - Prospective Studies MH - Single-Blind Method MH - Stroke/*therapy MH - *Stroke Rehabilitation MH - *Walking EDAT- 2012/03/02 06:00 MHDA- 2012/09/29 06:00 CRDT- 2012/03/02 06:00 PHST- 2012/03/02 06:00 [entrez] PHST- 2012/03/02 06:00 [pubmed] PHST- 2012/09/29 06:00 [medline] AID - 10.3109/09638288.2012.658952 [doi] PST - ppublish SO - Disabil Rehabil. 2012;34(19):1665-71. doi: 10.3109/09638288.2012.658952. Epub 2012 Mar 1.