PMID- 22393692
OWN - NLM
STAT- MEDLINE
DCOM- 20130114
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 29
IP  - 11
DP  - 2011 Nov
TI  - [Determination of commonly abused dyes in food by liquid chromatography-tandem 
      mass spectrometry].
PG  - 1062-9
AB  - A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed 
      for the determination of commonly abused dyes in candy, sirup, liquid milk and 
      fruit juice. The test sample was dissolved and diluted with water, then cleaned 
      up by polyamide solid phase extraction. The LC separation was performed on an 
      Agilent XDB-C18 column with 20 mmol/L ammonium acetate solution and acetonitrile 
      as the mobile phase in a gradient elution mode. The dyes were determined by MS/MS 
      in negative electrospray ionization mode, and quantified by matrix-matched 
      external standard method. The calibration curves showed good linearity in the 
      range of 0.5 - 50 mg/L with the correlation coefficients (r) greater than 0.99. 
      The limits of quantitation (S/N > 10) were 0.5 mg/kg, and the limits of detection 
      (S/N > 3) were 0.1 mg/kg. The recoveries of dyes in food samples at the three 
      spiked levels of 0.5, 5 and 50 mg/kg were in the range of 62.6% - 115.3% with the 
      relative standard deviations (RSDs) of 2.6% - 26.3%. The method can meet the 
      requirements for the determination of the dyes in food samples for import and 
      export inspection.
FAU - Yi, Xionghai
AU  - Yi X
AD  - Shanghai Entry-Exit Inspection and Quarantine Bureau, Shanghai 200135, China. 
      yixh@shciq.gov.cn
FAU - Deng, Xiaojun
AU  - Deng X
FAU - Yang, Huiqin
AU  - Yang H
FAU - Guo, Dehua
AU  - Guo D
FAU - Zhu, Jian
AU  - Zhu J
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Coloring Agents)
SB  - IM
MH  - Beverages/*analysis
MH  - Candy/analysis
MH  - Chromatography, Liquid/*methods
MH  - Coloring Agents/*analysis
MH  - Food Contamination/analysis
MH  - Tandem Mass Spectrometry/*methods
EDAT- 2012/03/08 06:00
MHDA- 2013/01/15 06:00
CRDT- 2012/03/08 06:00
PHST- 2012/03/08 06:00 [entrez]
PHST- 2012/03/08 06:00 [pubmed]
PHST- 2013/01/15 06:00 [medline]
PST - ppublish
SO  - Se Pu. 2011 Nov;29(11):1062-9.