PMID- 22397245
OWN - NLM
STAT- MEDLINE
DCOM- 20120329
LR  - 20151119
IS  - 0350-6134 (Print)
IS  - 0350-6134 (Linking)
VI  - 35
IP  - 4
DP  - 2011 Dec
TI  - Differential diagnostic performance of Rose Bengal Score Test in Sjogren's 
      syndrome patients.
PG  - 1105-13
AB  - Aim of the study was to evaluate the diagnostic performance of the Rose Bengal 
      score test for Sjogren's syndrome (SS), and to explore differences between other 
      tests and examinations. All participants were examined, including (but not 
      limited to) unstimulated (UWS) and stimulated (SWS) whole saliva, labial gland 
      biopsy (LGB or focus score), ophthalmologic questionnaire (ocular surface disease 
      index OSDI) and objective tests: Schirmer test 1 (Sch. 1), Schirmer test 2 
      (Sch.2), Tear Break-up Time (TBUT) test and Rose Bengal score (RBS). Data were 
      analyzed using Mann Whitney U-test, Receiver Operating Characteristic analysis, 
      with specificity and sensitivity calculations and Spearman's correlation test. 
      ROC curves showed a poor diagnostic performance of TBUT and OSDI. Sch. 1, Sch.2 
      and LGB all exhibited a high diagnostic performance. RBS exhibited the best 
      performance (sensitivity 100,00; specificity 100,00; AUC 1,000). Study reveals 
      the scarce reliability of TBUT, OSDI and Sch.1, and emphasizes RBS as the test of 
      choice in the SS diagnosis.
FAU - Knezovic, Igor
AU  - Knezovic I
AD  - University of Zagreb, Dubrava University Hospital, Department of Ophthalmology, 
      Zagreb, Croatia. i_knezovic@yahoo.com
FAU - Alajbeg, Ivan
AU  - Alajbeg I
FAU - Karlovic, Dalibor
AU  - Karlovic D
FAU - Pavan, Josip
AU  - Pavan J
FAU - Vrkic, Nada
AU  - Vrkic N
FAU - Biscan, Ana
AU  - Biscan A
LA  - eng
PT  - Journal Article
PL  - Croatia
TA  - Coll Antropol
JT  - Collegium antropologicum
JID - 8003354
RN  - 1ZPG1ELY14 (Rose Bengal)
SB  - IM
MH  - Female
MH  - Humans
MH  - Male
MH  - ROC Curve
MH  - *Rose Bengal
MH  - Sjogren's Syndrome/*diagnosis
EDAT- 2012/03/09 06:00
MHDA- 2012/03/30 06:00
CRDT- 2012/03/09 06:00
PHST- 2012/03/09 06:00 [entrez]
PHST- 2012/03/09 06:00 [pubmed]
PHST- 2012/03/30 06:00 [medline]
PST - ppublish
SO  - Coll Antropol. 2011 Dec;35(4):1105-13.