PMID- 22402900 OWN - NLM STAT- MEDLINE DCOM- 20120716 LR - 20211021 IS - 1433-0458 (Electronic) IS - 0017-6192 (Linking) VI - 60 IP - 3 DP - 2012 Mar TI - [Laryngopharyngeal reflux and larynx-related symptoms]. PG - 200-5 LID - 10.1007/s00106-011-2441-6 [doi] AB - BACKGROUND: Chronic hoarseness, globus sensation or mucous obstruction are among a wide range of symptoms possibly related to laryngopharyngeal reflux (LPR). METHOD AND RESULTS: A selective literature research was carried out using PubMed, in which original articles and reviews in German and English were included. Altogether, 2541 articles were found. Despite the large number of publications, there are still open questions regarding aspects of LPR. DISCUSSION: It can be assumed that refluxate reaching the larynx can damage it. Due to the fact that the symptoms possibly related to LPR can, however, be linked to other causes, a careful consideration of the patient's medical history is of the utmost importance, followed by mandatory laryngoscopy. Diagnostic procedures, such as the trial administration of proton pump inhibitors (PPI) or long-term pH measurement should be used selectively. Depending on the individual symptoms, breathing or voice therapy and/or PPI therapy might be useful. Lifestyle changes including dietary measures should also be contemplated. FAU - Ptok, M AU - Ptok M AD - Klinik und Poliklinik fur Phoniatrie und Padaudiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. Ptok.Martin@MH-Hannover.de FAU - Ptok, A AU - Ptok A LA - ger PT - English Abstract PT - Journal Article PT - Review TT - Laryngopharyngealer Reflux und kehlkopfassoziierte Beschwerden. PL - Germany TA - HNO JT - HNO JID - 2985099R RN - 0 (Proton Pump Inhibitors) SB - IM MH - Diet Therapy/methods MH - Hoarseness/*diagnosis/etiology/*prevention & control MH - Humans MH - Laryngitis/*diagnosis/etiology/*prevention & control MH - Laryngopharyngeal Reflux/complications/*diagnosis/*therapy MH - Proton Pump Inhibitors/*therapeutic use EDAT- 2012/03/10 06:00 MHDA- 2012/07/17 06:00 CRDT- 2012/03/10 06:00 PHST- 2012/03/10 06:00 [entrez] PHST- 2012/03/10 06:00 [pubmed] PHST- 2012/07/17 06:00 [medline] AID - 10.1007/s00106-011-2441-6 [doi] PST - ppublish SO - HNO. 2012 Mar;60(3):200-5. doi: 10.1007/s00106-011-2441-6.