PMID- 22404098 OWN - NLM STAT- MEDLINE DCOM- 20120822 LR - 20161125 IS - 1540-8175 (Electronic) IS - 0742-2822 (Linking) VI - 29 IP - 5 DP - 2012 May TI - Novel application of four-dimensional sonography with B-flow imaging and spatiotemporal image correlation in the assessment of fetal congenital heart defects. PG - 614-9 LID - 10.1111/j.1540-8175.2011.01639.x [doi] AB - AIMS: To evaluate the role of four-dimensional (4D) ultrasound with B-flow imaging and spatiotemporal image correlation (STIC) in the evaluation of normal fetal heart and congenital heart disease during pregnancy. METHODS: Volume data sets of the fetal heart were acquired with automated transverse and longitudinal sweeps of the anterior chest wall. We studied 31 normal fetuses and 28 fetuses with congenital heart disease (6 with double-outlet right ventricle, 5 with complete transposition of great arteries, 8 with tetralogy of Fallot, 3 with right aortic arch, 2 with persistent left superior vena cava, 3 with truncus arteriosus communis, and 1 with interruption of aortic arch) at gestation ages ranging from 18 to 39 weeks using transabdominal 4D B-flow sonography with STIC (4D BF-STIC). RESULTS: Four-dimensional BF-STIC demonstrated dynamic angiographic features in both normal and abnormal fetal hearts. Four-dimensional BF-STIC images could not be obtained in two normal fetuses at 18.9 and 35.6 weeks because of the high fetal heart rate and inappropriate fetal position. Of the other 29 fetuses all extracardiac vessels such as aorta, pulmonary artery, ductus arteriosus, inferior vena cava, and ductus venosus could be detected on reconstructed images. In seven normal cases, a 4D image was recorded to allow simultaneous visualization of all four pulmonary veins. In the 28 fetuses with cardiac anomalies, 4D sonography with B-flow imaging and STIC detected the "digital casts" of the outflow tracts, great arteries, and veins draining into the heart. These results demonstrate spatial relationship among these structures which provide important anatomical information. CONCLUSION: Four-dimensional BF-STIC provides a means of real time three-dimensional evaluation of fetal extracardiac hemodynamics in the second and third trimesters. This novel technique assists in the evaluation of fetal cardiac hemodynamics and may play an important role in future fetal cardiac research and in the identification of anatomical features of different congenital cardiac anomalies. CI - (c) 2012 Wiley Periodicals, Inc. FAU - Hongmei, Wu AU - Hongmei W AD - Department of Ultrasonography, Shengjing Hospital of China Medical University, Shenyang, China. FAU - Ying, Zhang AU - Ying Z FAU - Ailu, Cai AU - Ailu C FAU - Wei, Sun AU - Wei S LA - eng PT - Comparative Study PT - Journal Article DEP - 20120308 PL - United States TA - Echocardiography JT - Echocardiography (Mount Kisco, N.Y.) JID - 8511187 SB - IM MH - *Algorithms MH - Echocardiography, Four-Dimensional/*methods MH - Female MH - Heart Defects, Congenital/*diagnostic imaging MH - Humans MH - Image Enhancement/methods MH - Image Interpretation, Computer-Assisted/*methods MH - Imaging, Three-Dimensional/*methods MH - Male MH - Pregnancy MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Statistics as Topic MH - Ultrasonography, Prenatal/*methods EDAT- 2012/03/13 06:00 MHDA- 2012/08/23 06:00 CRDT- 2012/03/13 06:00 PHST- 2012/03/13 06:00 [entrez] PHST- 2012/03/13 06:00 [pubmed] PHST- 2012/08/23 06:00 [medline] AID - 10.1111/j.1540-8175.2011.01639.x [doi] PST - ppublish SO - Echocardiography. 2012 May;29(5):614-9. doi: 10.1111/j.1540-8175.2011.01639.x. Epub 2012 Mar 8.