PMID- 22405292
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20211021
IS  - 1755-7682 (Electronic)
IS  - 1755-7682 (Linking)
VI  - 5
DP  - 2012 Mar 9
TI  - Insights from magnetic resonance imaging of left ventricular non-compaction in 
      adults of North African descent.
PG  - 10
LID - 10.1186/1755-7682-5-10 [doi]
AB  - BACKGROUND: Left ventricular non-compaction (LVNC) is a recently recognized rare 
      disorder. Magnetic resonance imaging (MRI) may help to clarify the uncertainties 
      related to this genetic cardiomyopathy. Despite the fact that many articles have 
      been published concerning the use of MRI in the study of LVNC, there is a lack of 
      data describing the disease in the North African population. The aim of our study 
      is to clarify MRI findings of LVNC in North African patients. METHODS: In our 
      retrospective cohort, twelve patients (7 male, mean age 53 +/- 8 years) underwent 
      MRI for suspected LVNC. Correlations were investigated between the number of 
      non-compacted segments per patient and left ventricular ejection fraction (LVEF), 
      then between the number of non-compacted segments and left ventricular end 
      diastolic diameter. The presence or absence of late gadolinium enhancement (LGE) 
      was qualitatively determined for each left ventricular myocardial segment. 
      RESULTS: Non-compaction was more commonly observed at the apex, the anterior and 
      the lateral walls, especially on their apical and mid-cavity segments. 83% of 
      patients had impaired LVEF. There was no correlation between the number of 
      non-compacted segments per patient and LVEF (r = -0.361; p = 0.263), nor between 
      the number of non-compacted segments per patient and left ventricular end 
      diastolic diameter (r = 0.280; p = 0.377). LGE was observed in 22 left 
      ventricular segments. No association was found between the pattern of fibrosis 
      and non-compaction distribution (OR = 2.2, CI [0.91-5.55], p = 0.076). 
      CONCLUSION: The distribution of LVNC in North African patients does not differ 
      from other populations. Ventricular dysfunction is independent from the number of 
      non-compacted segments. Myocardial fibrosis is not limited to non-compacted areas 
      but can extend to compacted segments.
FAU - Lachhab, Amal
AU  - Lachhab A
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Doghmi, Nawal
AU  - Doghmi N
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Elfakir, Youssef
AU  - Elfakir Y
AD  - Radiology Nakhil Department, Agdal Clinic, Rabat, Morocco.
FAU - Taoussi, Omar
AU  - Taoussi O
AD  - Radiology Nakhil Department, Agdal Clinic, Rabat, Morocco.
FAU - Benyass, Aatef
AU  - Benyass A
AD  - Military Cardiology Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Haddour, Laila
AU  - Haddour L
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Zarzur, Jamila
AU  - Zarzur J
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Cherradi, Rhizlane
AU  - Cherradi R
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Fellat, Ibtissam
AU  - Fellat I
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Aouad, Aicha
AU  - Aouad A
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Ellouali, Fedoua
AU  - Ellouali F
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Asfalou, Ilyas
AU  - Asfalou I
AD  - Military Cardiology Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Elmajhad, Amin
AU  - Elmajhad A
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
FAU - Cherti, Mohamed
AU  - Cherti M
AD  - Cardiology B Department, Ibn Sina University Hospital, Rabat, Morocco.
LA  - eng
PT  - Journal Article
DEP - 20120309
PL  - England
TA  - Int Arch Med
JT  - International archives of medicine
JID - 101317943
PMC - PMC3327641
EDAT- 2012/03/13 06:00
MHDA- 2012/03/13 06:01
PMCR- 2012/03/09
CRDT- 2012/03/13 06:00
PHST- 2011/09/24 00:00 [received]
PHST- 2012/03/09 00:00 [accepted]
PHST- 2012/03/13 06:00 [entrez]
PHST- 2012/03/13 06:00 [pubmed]
PHST- 2012/03/13 06:01 [medline]
PHST- 2012/03/09 00:00 [pmc-release]
AID - 1755-7682-5-10 [pii]
AID - 10.1186/1755-7682-5-10 [doi]
PST - epublish
SO  - Int Arch Med. 2012 Mar 9;5:10. doi: 10.1186/1755-7682-5-10.