PMID- 22407255
OWN - NLM
STAT- MEDLINE
DCOM- 20121009
LR  - 20120507
IS  - 1538-9235 (Electronic)
IS  - 1040-5488 (Linking)
VI  - 89
IP  - 5
DP  - 2012 May
TI  - SD-OCT use in myopic retinoschisis pre- and post-vitrectomy.
PG  - 678-83
LID - 10.1097/OPX.0b013e31824eeaed [doi]
AB  - PURPOSE: To study the features of posterior retinoschisis in high myopia before 
      and after vitrectomy and its correlation with the visual outcome by 
      spectral-domain optical coherence tomography (SD-OCT). METHODS: In this 
      retrospective case series, 11 highly myopic eyes which underwent vitrectomy with 
      internal limiting membrane peeling and gas tamponade for retinoschisis during 
      June 2008 to December 2009 were followed up for 6 months. Visual acuity and 
      SD-OCT (Topcon 3D OCT-1000) examination were performed before surgery and 1, 3, 
      and 6 months after surgery. RESULTS: Retinoschisis within the outer, middle, and 
      inner layers was noted in six eyes, and foveal detachment was found in six eyes 
      by SD-OCT preoperatively. The inner and outer segment junctions of the 
      photoreceptor layer showed defects in all eyes. At 6 months postoperatively, the 
      retina had reattached and schisis resolved in 10 eyes. Two parafoveal holes were 
      noted in one eye after surgery. The best-corrected visual acuity increased from 
      0.15 to 0.8 in one eye, slightly improved in two eyes, and remained unchanged in 
      eight eyes. The continuity of inner segment-outer segment layer almost completely 
      recovered in the eye with best-corrected visual acuity of 0.8 while still showing 
      defects in the other 10 eyes. CONCLUSIONS: SD-OCT can clearly demonstrate the 
      morphological changes of retinoschisis. It provides important evidence as to the 
      advantage of vitrectomy with internal limiting membrane peeling and helps to 
      explain the visual outcome by documenting the recovery of the inner segment-outer 
      segment layer after surgery. An SD-OCT examination should be considered in 
      patients with high myopia and decreasing vision, with no obvious fundoscopic 
      findings.
FAU - Wang, Shiyuan
AU  - Wang S
AD  - Department of Ophthalmology, Xinhua Hospital, Shanghai JiaoTong University, 
      School of Medicine, Shanghai 200092, China.
FAU - Peng, Qing
AU  - Peng Q
FAU - Zhao, Peiquan
AU  - Zhao P
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Optom Vis Sci
JT  - Optometry and vision science : official publication of the American Academy of 
      Optometry
JID - 8904931
SB  - IM
MH  - Adult
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myopia/*complications/diagnosis/surgery
MH  - Photoreceptor Cells/*pathology
MH  - Postoperative Period
MH  - Preoperative Period
MH  - Prognosis
MH  - Recovery of Function
MH  - Retinoschisis/*diagnosis/etiology/surgery
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Time Factors
MH  - Tomography, Optical Coherence/*methods
MH  - Visual Acuity
MH  - *Vitrectomy
EDAT- 2012/03/13 06:00
MHDA- 2012/10/10 06:00
CRDT- 2012/03/13 06:00
PHST- 2012/03/13 06:00 [entrez]
PHST- 2012/03/13 06:00 [pubmed]
PHST- 2012/10/10 06:00 [medline]
AID - 10.1097/OPX.0b013e31824eeaed [doi]
PST - ppublish
SO  - Optom Vis Sci. 2012 May;89(5):678-83. doi: 10.1097/OPX.0b013e31824eeaed.