PMID- 22410034
OWN - NLM
STAT- MEDLINE
DCOM- 20120801
LR  - 20191210
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 44
IP  - 2
DP  - 2012 Mar
TI  - Cardiac output derived from arterial pressure waveform analysis in patients 
      undergoing liver transplantation: validity of a third-generation device.
PG  - 424-8
LID - 10.1016/j.transproceed.2011.12.036 [doi]
AB  - BACKGROUND: Hemodynamic monitoring is essential to a successful liver 
      transplantation procedure. FloTrac, a hemodynamic monitor that uses 
      arterial-waveform-based pulse contour analysis for cardiac output (CO) 
      measurement, has proven useful in many clinical settings. One of the primary foci 
      of FloTrac's recent third-generation software upgrade was improving its accuracy 
      in low systemic vascular resistance status. We evaluated the accuracy of the 
      upgraded FloTrac monitor during liver transplantation. MATERIALS AND METHODS: 
      Twenty-eight patients undergoing liver transplantation were enrolled in the 
      study. Two sets of CO were measured with a radial arterial line connected to a 
      FloTrac monitor (COFT) and a pulmonary artery catheter connected to a continuous 
      cardiac output Vigilence monitor (COPAC). Simultaneous CO measurement was 
      performed and recorded every 5 minutes throughout the surgery. Bland-Altman 
      analysis was used to estimate the accuracy. The comparative method and reference 
      method were considered interchangeable if the limits of agreement did not exceed 
      a threshold set a priori at the greater of +/-1 L/min, or a percentage error of 
      lesser than 30%. RESULTS: In all, 3234 paired data were collected. The bias was 
      -0.8 L/min and the limits of agreements were -5.6 to 4.0 L/min. Percentage error 
      was 75%. Regression analysis of the systemic vascular resistance index (SVRI) and 
      the bias between COPAC and COFT showed that the bias was inversely related to the 
      SVRI [r2=0.49; P<.001, y=-32.1983+9.9978 Log(x)]. CONCLUSIONS: Despite a software 
      upgrade, the effectiveness of the FloTrac artery-derived cardiac output monitor 
      for CO measurement during liver transplantation remains limited.
CI  - Copyright A(c) 2012 Elsevier Inc. All rights reserved.
FAU - Su, B C
AU  - Su BC
AD  - Department of Anesthesia, Chang Gung Memorial Hospital-Linkou, and College of 
      Medicine, Chang Gung University, Kwei-Shan Taoyuan, Taiwan.
FAU - Tsai, Y F
AU  - Tsai YF
FAU - Chen, C Y
AU  - Chen CY
FAU - Yu, H P
AU  - Yu HP
FAU - Yang, M W
AU  - Yang MW
FAU - Lee, W C
AU  - Lee WC
FAU - Lin, C C
AU  - Lin CC
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Validation Study
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
SB  - IM
MH  - Adult
MH  - Aged
MH  - Bias
MH  - *Blood Pressure
MH  - *Blood Pressure Monitors
MH  - *Cardiac Output
MH  - Catheterization, Swan-Ganz
MH  - Equipment Design
MH  - Female
MH  - Humans
MH  - Liver Cirrhosis/physiopathology/*surgery
MH  - *Liver Transplantation
MH  - Male
MH  - Middle Aged
MH  - Monitoring, Intraoperative/*instrumentation
MH  - Predictive Value of Tests
MH  - *Radial Artery
MH  - Regression Analysis
MH  - Reproducibility of Results
MH  - Software
MH  - Taiwan
MH  - Time Factors
MH  - Vascular Resistance
EDAT- 2012/03/14 06:00
MHDA- 2012/08/02 06:00
CRDT- 2012/03/14 06:00
PHST- 2012/03/14 06:00 [entrez]
PHST- 2012/03/14 06:00 [pubmed]
PHST- 2012/08/02 06:00 [medline]
AID - S0041-1345(11)01698-8 [pii]
AID - 10.1016/j.transproceed.2011.12.036 [doi]
PST - ppublish
SO  - Transplant Proc. 2012 Mar;44(2):424-8. doi: 10.1016/j.transproceed.2011.12.036.