PMID- 22416454
OWN - NLM
STAT- MEDLINE
DCOM- 20120717
LR  - 20120315
IS  - 0047-1860 (Print)
IS  - 0047-1860 (Linking)
VI  - 60
IP  - 1
DP  - 2012 Jan
TI  - [Case with intrauterine fetus death: interphase fluorescence in situ 
      hybridization using buccal cells is useful for examining chromosomal 
      abnormalities when placental villus not available].
PG  - 32-6
AB  - The proband was a male fetus who died at 18 weeks of gestation. The fetus had 
      growth retardation, hydrocephalus, exophthalmos, and micrognathia. The placental 
      villus was not available. We performed interphase fluorescence in situ 
      hybridization (FISH) using buccal cells of the fetus. The FISH using centromere 
      specific probes for chromosome 7, 8 and 18, and RB1 gene (13q14)-specific probe 
      showed three signals for each chromosome. The sex chromosome composition was XXY 
      by FISH using centromere-specific probes for X and Y chromosomes. Thus, the fetus 
      was diagnosed with triploidy syndrome. This report suggested that interphase FISH 
      using buccal cells is useful for examining chromosomal abnormalities in 
      intrauterine fetal death when placental villus is not available.
FAU - Takezawa, Yuka
AU  - Takezawa Y
FAU - Kosho, Tomoki
AU  - Kosho T
FAU - Matsuda, Kazuyuki
AU  - Matsuda K
FAU - Taira, Chiaki
AU  - Taira C
FAU - Ito, Yurika
AU  - Ito Y
FAU - Hidaka, Eiko
AU  - Hidaka E
FAU - Sugano, Mitsutoshi
AU  - Sugano M
FAU - Narumi, Yoko
AU  - Narumi Y
FAU - Mizuuchi, Asako
AU  - Mizuuchi A
FAU - Kobara, Hisanori
AU  - Kobara H
FAU - Wakui, Keiko
AU  - Wakui K
FAU - Okumura, Nobuo
AU  - Okumura N
FAU - Fukushima, Yoshimitsu
AU  - Fukushima Y
FAU - Honda, Takayuki
AU  - Honda T
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Rinsho Byori
JT  - Rinsho byori. The Japanese journal of clinical pathology
JID - 2984781R
SB  - IM
MH  - Adult
MH  - Chorionic Villi
MH  - Chromosome Aberrations/*embryology
MH  - Chromosomes, Human/genetics
MH  - Female
MH  - Fetal Death/*etiology
MH  - Genetic Counseling
MH  - Humans
MH  - In Situ Hybridization/*methods
MH  - Male
MH  - Mouth Mucosa/*cytology/*embryology
MH  - Pregnancy
MH  - Syndrome
MH  - *Triploidy
EDAT- 2012/03/16 06:00
MHDA- 2012/07/18 06:00
CRDT- 2012/03/16 06:00
PHST- 2012/03/16 06:00 [entrez]
PHST- 2012/03/16 06:00 [pubmed]
PHST- 2012/07/18 06:00 [medline]
PST - ppublish
SO  - Rinsho Byori. 2012 Jan;60(1):32-6.