PMID- 22418560 OWN - NLM STAT- MEDLINE DCOM- 20121003 LR - 20181023 IS - 1094-4087 (Electronic) IS - 1094-4087 (Linking) VI - 20 IP - 6 DP - 2012 Mar 12 TI - Common approach for compensation of axial motion artifacts in swept-source OCT and dispersion in Fourier-domain OCT. PG - 6761-76 LID - 10.1364/OE.20.006761 [doi] AB - Swept-source optical coherence tomography (SS-OCT) is sensitive to sample motion during the wavelength sweep, which leads to image blurring and image artifacts. In line-field and full-field SS-OCT parallelization is achieved by using a line or area detector, respectively. Thus, approximately 1000 lines or images at different wavenumbers are acquired. The sweep duration is identically with the acquisition time of a complete B-scan or volume, rendering parallel SS-OCT more sensitive to motion artifacts than scanning OCT. The effect of axial motion on the measured spectra is similar to the effect of non-balanced group velocity dispersion (GVD) in the interferometer arms. It causes the apparent optical path lengths in the sample arm to vary with the wavenumber. Here we propose the cross-correlation of sub-bandwidth reconstructions (CCSBR) as a new algorithm that is capable of detecting and correcting the artifacts induced by axial motion in line-field or full-field SS-OCT as well as GVD mismatch in any Fourier-domain OCT (FD-OCT) setup. By cross-correlating images which were reconstructed from a limited spectral range of the interference signal, a phase error is determined which is used to correct the spectral modulation prior to the calculation of the A-scans. Performance of the algorithm is demonstrated on in vivo full-field SS-OCT images of skin and scanning FD-OCT of skin and retina. FAU - Hillmann, Dierck AU - Hillmann D AD - Thorlabs GmbH, Maria-Goeppert-Str. 1, 23562 Lubeck, Germany. dhillmann@thorlabs.com FAU - Bonin, Tim AU - Bonin T FAU - Luhrs, Christian AU - Luhrs C FAU - Franke, Gesa AU - Franke G FAU - Hagen-Eggert, Martin AU - Hagen-Eggert M FAU - Koch, Peter AU - Koch P FAU - Huttmann, Gereon AU - Huttmann G LA - eng PT - Journal Article PL - United States TA - Opt Express JT - Optics express JID - 101137103 SB - IM MH - *Algorithms MH - *Artifacts MH - Fourier Analysis MH - Image Enhancement/*methods MH - Image Interpretation, Computer-Assisted/*methods MH - Motion MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Tomography, Optical Coherence/*methods EDAT- 2012/03/16 06:00 MHDA- 2012/10/04 06:00 CRDT- 2012/03/16 06:00 PHST- 2012/03/16 06:00 [entrez] PHST- 2012/03/16 06:00 [pubmed] PHST- 2012/10/04 06:00 [medline] AID - 230221 [pii] AID - 10.1364/OE.20.006761 [doi] PST - ppublish SO - Opt Express. 2012 Mar 12;20(6):6761-76. doi: 10.1364/OE.20.006761.