PMID- 22419299
OWN - NLM
STAT- MEDLINE
DCOM- 20120607
LR  - 20181201
IS  - 1469-493X (Electronic)
IS  - 1361-6137 (Linking)
IP  - 3
DP  - 2012 Mar 14
TI  - WITHDRAWN: Hyperbaric oxygen therapy for promoting fracture healing and treating 
      fracture non-union.
PG  - CD004712
LID - 10.1002/14651858.CD004712.pub3 [doi]
AB  - BACKGROUND: Hyperbaric oxygen therapy (HBOT) consists of intermittently 
      administering 100% oxygen at pressures greater than one atmosphere absolute (ATA) 
      in a pressure vessel. This technology has been used to treat a variety of 
      diseases and has been described as helping patients who have delayed healing or 
      established non-union of bony fractures. OBJECTIVES: The aim of this review was 
      to assess the evidence for the benefit of hyperbaric oxygen treatment (HBOT) for 
      the treatment of delayed bony healing and established non-union of bony 
      fractures. SEARCH METHODS: We searched the Cochrane Bone, Joint and Muscle Trauma 
      Group Specialised Register (April 2008), the Cochrane Register of Controlled 
      Trials (CENTRAL) (The Cochrane Library Issue 2, 2008), MEDLINE (OVID 1966 to 
      April week 3, 2008), CINAHL (OVID 1982 to April week 3, 2008), EMBASE (OVID 1980 
      to week 17 2008), the locally developed Database of Randomised Controlled Trials 
      in Hyperbaric Medicine (available at www.hboevidence.com) from inception to May 
      2008, and reference lists of articles. SELECTION CRITERIA: We aimed to include 
      all randomised controlled trials that compared the effect of HBOT with no HBOT 
      (no treatment or sham). DATA COLLECTION AND ANALYSIS: We planned independent data 
      collection by two authors using standardised forms. MAIN RESULTS: No trials met 
      the inclusion criteria. We excluded one trial that compared HBOT with no 
      treatment because no clinical outcomes were reported. AUTHORS' CONCLUSIONS: This 
      systematic review failed to locate any relevant clinical evidence to support or 
      refute the effectiveness of HBOT for the management of delayed union or 
      established non-union of bony fractures. Good quality clinical trials are needed 
      to define the role, if any, of HBOT in the treatment of these injuries.
FAU - Bennett, Michael H
AU  - Bennett MH
AD  - Department of Anaesthesia, Prince of Wales Hospital, Barker Street, Randwick, 
      NSW, 2031,Australia. m.bennett@unsw.edu.au. s9400356@unsw.edu.au.
FAU - Stanford, Ralph E
AU  - Stanford RE
FAU - Turner, Robert
AU  - Turner R
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20120314
PL  - England
TA  - Cochrane Database Syst Rev
JT  - The Cochrane database of systematic reviews
JID - 100909747
SB  - IM
UOF - Cochrane Database Syst Rev. 2005;(1):CD004712. PMID: 15674962
UIN - Cochrane Database Syst Rev. 2012;11:CD004712. PMID: 23152225
MH  - *Fracture Healing
MH  - Fractures, Ununited/physiopathology/*therapy
MH  - Humans
MH  - Hyperbaric Oxygenation/*methods
EDAT- 2012/03/16 06:00
MHDA- 2012/06/08 06:00
CRDT- 2012/03/16 06:00
PHST- 2012/03/16 06:00 [entrez]
PHST- 2012/03/16 06:00 [pubmed]
PHST- 2012/06/08 06:00 [medline]
AID - 10.1002/14651858.CD004712.pub3 [doi]
PST - epublish
SO  - Cochrane Database Syst Rev. 2012 Mar 14;(3):CD004712. doi: 
      10.1002/14651858.CD004712.pub3.