PMID- 22420531
OWN - NLM
STAT- MEDLINE
DCOM- 20120430
LR  - 20120316
IS  - 1365-3083 (Electronic)
IS  - 0300-9475 (Linking)
VI  - 75
IP  - 4
DP  - 2012 Apr
TI  - IgE sensitization to the fish parasite Anisakis simplex in a Norwegian 
      population: a pilot study.
PG  - 431-5
LID - 10.1111/j.1365-3083.2012.02670.x [doi]
AB  - The reports on fish parasite Anisakis simplex allergy have increased in countries 
      with high fish consumption in the last decade. In Norway, a high consumption 
      country, the prevalence of immunoglobulin E (IgE) sensitization to A. simplex was 
      still unknown. Thus, our objective was to investigate the sensitization 
      prevalence in this country. At the Haukeland University Hospital, Bergen, Norway, 
      two main groups of surplus serum samples were collected: one from newly recruited 
      blood donors (BDO) and the other from the Allergy laboratory (ALL) after 
      analysing IgE and IgE antibodies. The latter was divided into three series: one 
      containing unsorted sera and two sorted by either Phadiatop((R)) >/=0.35 kU(A)/l or 
      total IgE >/=1000 kU/l. The sera were analysed for total IgE and IgE antibodies 
      against A. simplex, shrimp, house dust mite (HDM), cod and cross-reactive 
      carbohydrates (CCDs). The prevalence of IgE sensitization to A. simplex was 2.0%, 
      2.2% and 6.6% in BDO, the unsorted and Phadiatop((R)) positive serum groups, 
      respectively. A considerable degree of cross-sensitization to shrimp and HDM is 
      further suggested. Unspecific binding because of high total IgE or by binding to 
      CCDs seemed to play a minor role. The prevalence of IgE sensitization to A. 
      simplex appears to be lower in a Norwegian population than in other high 
      fish-consuming countries, but might still be overestimated owing to 
      cross-sensitization.
CI  - (c) 2011 The Authors. Scandinavian Journal of Immunology (c) 2011 Blackwell 
      Publishing Ltd.
FAU - Lin, A H
AU  - Lin AH
AD  - National Institute of Nutrition and Seafood Research, Bergen, Norway. 
      aung.lin@med.uib.no
FAU - Florvaag, E
AU  - Florvaag E
FAU - Van Do, T
AU  - Van Do T
FAU - Johansson, S G O
AU  - Johansson SG
FAU - Levsen, A
AU  - Levsen A
FAU - Vaali, K
AU  - Vaali K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Scand J Immunol
JT  - Scandinavian journal of immunology
JID - 0323767
RN  - 0 (Antibodies, Helminth)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Animals
MH  - Anisakis/*immunology
MH  - Antibodies, Helminth/*immunology
MH  - Cross Reactions
MH  - Fish Products/adverse effects/parasitology
MH  - Fishes/*parasitology
MH  - Food Hypersensitivity/epidemiology/immunology/parasitology
MH  - Immunoglobulin E/*immunology
MH  - Norway/epidemiology
MH  - Pilot Projects
MH  - Prevalence
EDAT- 2012/03/17 06:00
MHDA- 2012/05/01 06:00
CRDT- 2012/03/17 06:00
PHST- 2012/03/17 06:00 [entrez]
PHST- 2012/03/17 06:00 [pubmed]
PHST- 2012/05/01 06:00 [medline]
AID - 10.1111/j.1365-3083.2012.02670.x [doi]
PST - ppublish
SO  - Scand J Immunol. 2012 Apr;75(4):431-5. doi: 10.1111/j.1365-3083.2012.02670.x.