PMID- 22420632
OWN - NLM
STAT- MEDLINE
DCOM- 20120807
LR  - 20221207
IS  - 1520-5851 (Electronic)
IS  - 0013-936X (Linking)
VI  - 46
IP  - 8
DP  - 2012 Apr 17
TI  - Exposure to toxic metals and persistent organic pollutants in Inuit children 
      attending childcare centers in Nunavik, Canada.
PG  - 4614-23
LID - 10.1021/es203622v [doi]
AB  - Arctic populations are exposed to substantial levels of environmental 
      contaminants that can negatively affect children's health and development. 
      Moreover, emerging contaminants have never been assessed in Inuit children. In 
      this study, we document the biological exposure to toxic metals and legacy and 
      emerging persistent organic pollutants (POPs) of 155 Inuit children (mean age 
      25.2 months) attending childcare centers in Nunavik. Blood samples were analyzed 
      to determine concentrations of mercury, lead, polychlorinated biphenyls (PCBs), 
      pesticides, brominated flame retardants [e.g., polybrominated diphenyl ethers 
      (PBDEs)] and perfluoroalkyl and polyfluoroalkyl substances [PFASs; e.g. 
      perfluorooctanesulfonate (PFOS) and perfluorooctane (PFOA)]. Lead [geometric mean 
      (GM) 0.08 mumol/L], PCB-153 (GM 22.2 ng/g of lipid), BDE-47 (GM 184 ng/g of 
      lipid), PFOS (GM 3369 ng/L), and PFOA (GM 1617 ng/L) were detected in all 
      samples. Mercury (GM 9.8 nmol/L) was detected in nearly all blood samples (97%). 
      Levels of metals and legacy POPs are consistent with the decreasing trend 
      observed in Nunavik and in the Arctic. PBDE levels were higher than those 
      observed in many children and adolescents around the world but lower than those 
      reported in some U.S. cities. PFOS were present in lower concentrations than in 
      Nunavimmiut adults. There is a clear need for continued biomonitoring of blood 
      contaminant levels in this population, particularly for PBDEs and PFASs.
FAU - Turgeon O'Brien, Huguette
AU  - Turgeon O'Brien H
AD  - Groupe d'etudes en nutrition publique, Departement des sciences des aliments et 
      de nutrition, Universite Laval, Quebec, Quebec, Canada. 
      huguette.turgeon-obrien@fsaa.ulaval.ca
FAU - Blanchet, Rosanne
AU  - Blanchet R
FAU - Gagne, Doris
AU  - Gagne D
FAU - Lauziere, Julie
AU  - Lauziere J
FAU - Vezina, Carole
AU  - Vezina C
FAU - Vaissiere, Emilie
AU  - Vaissiere E
FAU - Ayotte, Pierre
AU  - Ayotte P
FAU - Dery, Serge
AU  - Dery S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120402
PL  - United States
TA  - Environ Sci Technol
JT  - Environmental science & technology
JID - 0213155
RN  - 0 (Environmental Pollutants)
RN  - 0 (Flame Retardants)
RN  - 0 (Fluorocarbons)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 2P299V784P (Lead)
RN  - FXS1BY2PGL (Mercury)
SB  - IM
EIN - Environ Sci Technol. 2012 Jul 17;46(14):7926
MH  - Child Day Care Centers
MH  - Child, Preschool
MH  - Environmental Monitoring
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Flame Retardants/analysis
MH  - Fluorocarbons/blood
MH  - Halogenated Diphenyl Ethers/blood
MH  - Humans
MH  - Hydrocarbons, Chlorinated/blood
MH  - Infant
MH  - Inuit
MH  - Lead/blood
MH  - Male
MH  - Mercury/blood
MH  - Pesticides/blood
MH  - Quebec
EDAT- 2012/03/17 06:00
MHDA- 2012/08/08 06:00
CRDT- 2012/03/17 06:00
PHST- 2012/03/17 06:00 [entrez]
PHST- 2012/03/17 06:00 [pubmed]
PHST- 2012/08/08 06:00 [medline]
AID - 10.1021/es203622v [doi]
PST - ppublish
SO  - Environ Sci Technol. 2012 Apr 17;46(8):4614-23. doi: 10.1021/es203622v. Epub 2012 
      Apr 2.