PMID- 22422539
OWN - NLM
STAT- MEDLINE
DCOM- 20121023
LR  - 20211021
IS  - 1555-905X (Electronic)
IS  - 1555-9041 (Print)
IS  - 1555-9041 (Linking)
VI  - 7
IP  - 5
DP  - 2012 May
TI  - Pedometer-assessed physical activity in children and young adults with CKD.
PG  - 720-6
LID - 10.2215/CJN.06330611 [doi]
AB  - BACKGROUND AND OBJECTIVES: Data on physical activity are limited in children with 
      CKD. The objectives of this study were to measure the level and correlates of 
      physical activity in children and young adults with CKD and to determine the 
      association of physical activity with physical performance and physical 
      functioning. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Physical activity was 
      measured for 7 days using pedometers; physical performance was measured by the 
      6-minute walk distance (6MWD) and physical functioning with the PedsQL 4.0. 
      RESULTS: Study participants were 44 patients 7-20 years of age who had CKD stage 
      1-4 (n=12), had ESRD and were undergoing dialysis (n=7), or had undergone kidney 
      transplantation (n=25). Participants were very sedentary; they walked 6218 
      (interquartile range, 3637, 9829) steps per day, considerably less than 
      recommended. Physical activity did not differ among participants in the CKD stage 
      1-4, ESRD, and transplant groups. Females were less active than males (P<0.01), 
      and physical activity was 44% lower among young adults (18-20 years) than younger 
      participants (P<0.05). Physical activity was associated positively with maternal 
      education and hemoglobin concentration and inversely with body mass index. 
      Respective 6MWD in males and females was 2 and approximately 4 SDs below 
      expected. Low levels of physical activity were associated with poor physical 
      performance and physical functioning, after adjustment for age, sex, and body 
      mass index. CONCLUSIONS: In most participants with CKD, physical activity was 
      considerably below recommended levels. Future studies are needed to determine 
      whether increasing physical activity can improve physical performance and 
      physical functioning.
FAU - Akber, Aalia
AU  - Akber A
AD  - Department of Pediatrics, Division of Pediatric Nephrology, University of 
      California, San Francisco, San Francisco, California, USA.
FAU - Portale, Anthony A
AU  - Portale AA
FAU - Johansen, Kirsten L
AU  - Johansen KL
LA  - eng
GR  - K24 DK085153/DK/NIDDK NIH HHS/United States
GR  - T32 DK007219/DK/NIDDK NIH HHS/United States
GR  - UL1 RR024131/RR/NCRR NIH HHS/United States
GR  - K24DK085153/DK/NIDDK NIH HHS/United States
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20120315
PL  - United States
TA  - Clin J Am Soc Nephrol
JT  - Clinical journal of the American Society of Nephrology : CJASN
JID - 101271570
RN  - 0 (Hemoglobins)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Body Mass Index
MH  - Child
MH  - Exercise Test
MH  - Female
MH  - Hemoglobins
MH  - Humans
MH  - Kidney Failure, Chronic/physiopathology/therapy
MH  - Kidney Transplantation
MH  - Male
MH  - Multivariate Analysis
MH  - Peritoneal Dialysis
MH  - Renal Dialysis
MH  - Renal Insufficiency, Chronic/*physiopathology/therapy
MH  - Self Report
MH  - *Task Performance and Analysis
MH  - Walking/*physiology
MH  - Young Adult
PMC - PMC3338276
EDAT- 2012/03/17 06:00
MHDA- 2012/10/24 06:00
PMCR- 2013/05/01
CRDT- 2012/03/17 06:00
PHST- 2012/03/17 06:00 [entrez]
PHST- 2012/03/17 06:00 [pubmed]
PHST- 2012/10/24 06:00 [medline]
PHST- 2013/05/01 00:00 [pmc-release]
AID - CJN.06330611 [pii]
AID - 06330611 [pii]
AID - 10.2215/CJN.06330611 [doi]
PST - ppublish
SO  - Clin J Am Soc Nephrol. 2012 May;7(5):720-6. doi: 10.2215/CJN.06330611. Epub 2012 
      Mar 15.