PMID- 22423609
OWN - NLM
STAT- MEDLINE
DCOM- 20120823
LR  - 20151119
IS  - 1366-5804 (Electronic)
IS  - 1354-750X (Linking)
VI  - 17
IP  - 3
DP  - 2012 May
TI  - Innate immunity markers in culprit plaques of acute myocardial infarction or 
      stable angina.
PG  - 209-15
LID - 10.3109/1354750X.2011.651158 [doi]
AB  - We analyzed the innate immunity markers, C-reactive protein (CRP), serum amyloid 
      P component (SAP) and pentraxin-3 (PTX-3), and metalloproteinase-9 (MMP-9) in 
      coronary atherectomy tissues obtained from patients with acute ST elevation 
      myocardial infarction (STEMI) (n=27) or stable angina (n=15). The relative areas 
      immunopositive for CRP and SAP were similar in the two groups. In contrast, the 
      proportion of areas immunopositive for PTX-3 and MMP-9 was higher in the STEMI 
      group, compared to the stable angina group. PTX-3 or MMP-9-stained areas largely 
      overlapped with those positive for CD68. We concluded that PTX-3 plays a role in 
      the pathogenesis of STEMI.
FAU - Lee, Cheol Whan
AU  - Lee CW
AD  - Department of Medicine, Asan Medical Center, Seoul, Republic of Korea.
FAU - Hwang, Ilseon
AU  - Hwang I
FAU - Park, Chan-Sik
AU  - Park CS
FAU - Lee, Hyangsin
AU  - Lee H
FAU - Park, Duk-Woo
AU  - Park DW
FAU - Kang, Su-Jin
AU  - Kang SJ
FAU - Lee, Seung-Whan
AU  - Lee SW
FAU - Kim, Young-Hak
AU  - Kim YH
FAU - Park, Seong-Wook
AU  - Park SW
FAU - Park, Seung-Jung
AU  - Park SJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120317
PL  - England
TA  - Biomarkers
JT  - Biomarkers : biochemical indicators of exposure, response, and susceptibility to 
      chemicals
JID - 9606000
RN  - 0 (Biomarkers)
SB  - IM
MH  - Aged
MH  - Angina Pectoris/*blood
MH  - Biomarkers/*blood
MH  - Female
MH  - Fluorescent Antibody Technique
MH  - Humans
MH  - *Immunity, Innate
MH  - Immunohistochemistry
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*blood
EDAT- 2012/03/20 06:00
MHDA- 2012/08/24 06:00
CRDT- 2012/03/20 06:00
PHST- 2012/03/20 06:00 [entrez]
PHST- 2012/03/20 06:00 [pubmed]
PHST- 2012/08/24 06:00 [medline]
AID - 10.3109/1354750X.2011.651158 [doi]
PST - ppublish
SO  - Biomarkers. 2012 May;17(3):209-15. doi: 10.3109/1354750X.2011.651158. Epub 2012 
      Mar 17.